Recombinant Mouse Stem Cell Factor/SCF/c-Kit Ligand, 小鼠蛋白Stem Cell Factor/SCF/c-Kit Ligand

Recombinant Mouse Stem Cell Factor/SCF/c-Kit Ligand, 小鼠蛋白Stem Cell Factor/SCF/c-Kit Ligand

参考价:¥935
供货周期: 一周
品牌: 爱必信
规格: 10ug
货号: abs04199
CAS号:
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产品描述:

产品名称:Recombinant Mouse Stem Cell Factor/SCF/c-Kit Ligand

描述:

Recombinant Mouse Stem Cell Factor is produced by our E.coli expression system and the target gene encoding Lys26-Ala189 is expressed.

氨基酸序列: MKEICGNPVTDNVKDITKLVANLPNDYMITLNYVAGMDVLPSHCWLRDMVIQLSLSLTTLLDKFS NISEGLSNYSIIDKLGKIVDDLVLCMEENAPKNIKESPKRPETRSFTPEEFFSIFNRSIDAFKDF MVASDTSDCVLSSTLGPEKDSRVSVTKPFMLPPVA

背景说明: Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5.

别名: Kit ligand,Hematopoietic growth factor KL,Mast cell growth factor,MGF,Steel factor,Stem cell factor,SCF

Accession: P20826

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Escherichia coli.

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

活性: Measured by the dose-dependent stimulation of TF-1 cells. The ED50 for this effect is typically 4-7 ng/mL.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

形态: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

储存/保存方法: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs04199   Recombinant Mouse Stem Cell Factor/SCF/c-Kit Ligand   10ug   935.00   立即咨询
  abs04199   Recombinant Mouse Stem Cell Factor/SCF/c-Kit Ligand   50ug   2090.00   立即咨询
  abs04199   Recombinant Mouse Stem Cell Factor/SCF/c-Kit Ligand   500ug   9429.00   立即咨询
  abs04199   Recombinant Mouse Stem Cell Factor/SCF/c-Kit Ligand   1mg   14080.00   立即咨询

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