Recombinant Human TRAIL/TNFSF10/CD253 (Arg115-Gly281), 人蛋白TRAIL/TNFSF10/CD253 (Arg115-Gly281)|10ug|abs04233-爱必信(上海)生物科技有限公司

Recombinant Human TRAIL/TNFSF10/CD253 (Arg115-Gly281), 人蛋白TRAIL/TNFSF10/CD253 (Arg115-Gly281)

参考价：¥420

供货周期：

一周

品牌：

爱必信

规格：

10ug

货号：

abs04233

CAS号：

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产品描述：

产品名称：Recombinant Human TRAIL/TNFSF10/CD253 (Arg115-Gly281)

背景说明: Human TNFSF10 is a type II transmembrane protein with an intracellular N-terminus and a ‘TNF homology domain’ (THD) at the extracellular C terminus. TNFSF10 can interact with several distinct receptors. Two of these receptors that belongs to TNFR superfamily, DR4 (TRAIL-R1) and DR5 (TRAIL-R2/TRICK2), are plasma membrane proteins containing intracellular death domains essential for activating apoptosis. TNFSF10 is promising for cancer therapy because it is cytotoxic and activates apoptosis in the majority of malignant cells, but not in normal cells.

描述:

Recombinant Human TNF-Related Apoptosis-Inducing Ligand is produced by our E.coli expression system and the target gene encoding Arg115-Gly281 is expressed.

氨基酸序列: MRERGPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHE KGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLYSIY QGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG

别名: Tumor Necrosis Factor Ligand Superfamily Member 10, Apo-2 Ligand, Apo-2L, TNF-Related Apoptosis-Inducing Ligand, Protein TRAIL, CD253, TNFSF10, APO2L, TRAIL

Accession: P50591

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Escherichia coli.

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

活性: Measured by the cytolysis of murine L929 cells in the presence of Actinomycin D. The ED50 for this effect less than 30 ng/ml.

形态: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 250mM Nacl, pH7.5.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

储存/保存方法: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04233	Recombinant Human TRAIL/TNFSF10/CD253 (Arg115-Gly281)	10ug	420.00	立即咨询
abs04233	Recombinant Human TRAIL/TNFSF10/CD253 (Arg115-Gly281)	50ug	1176.00	立即咨询
abs04233	Recombinant Human TRAIL/TNFSF10/CD253 (Arg115-Gly281)	500ug	5166.00	立即咨询
abs04233	Recombinant Human TRAIL/TNFSF10/CD253 (Arg115-Gly281)	1mg	7040.00	立即咨询

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