Recombinant Human Melanoma Inhibitory Activity Protein/MIA (C-6His), 人蛋白Melanoma Inhibitory Activity Protein/MIA (C-6His)|10ug|abs04307-爱必信(上海)生物科技有限公司

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产品描述：

产品名称：Recombinant Human Melanoma Inhibitory Activity Protein/MIA (C-6His)

描述: Recombinant Human Melanoma Inhibitory Activity Protein is produced by our E.coli expression system and the target gene encoding Gly25-Gln131 is expressed with a 6His tag at the C-terminus.

氨基酸序列: MGPMPKLADRKLCADQECSHPISMAVALQDYMAPDCRFLTIHRGQVVYVFSKLKGRGRLFWGGSV QGDYYGDLAARLGYFPSSIVREDQTLKPGKVDVKTDKWDFYCQLEHHHHHH

背景说明: Melanoma Inhibitory Activity Protein (MIA) is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells, which was the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family: MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA acts as a potent tumor cell growth inhibitor for malignant melanoma cells and some other neuroectodermal tumors, including gliomas, in an autocrine fashion and promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. The protein MIA has been shown to represent a very sensitive and specific serum marker for systemic malignant melanoma that might be useful for staging of primary melanomas, detection of progression from localized to metastatic disease during follow-up, and monitoring therapy of advanced melanomas. Elevated levels of MIA may represent a clinically useful marker for diagnosis of melanoma metastasis as well as a potential marker for rheumatoid arthritis.

别名: Melanoma-Derived Growth Regulatory Protein, Melanoma Inhibitory Activity Protein, MIA

Accession: Q16674

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Escherichia coli.

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

储存/保存方法: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04307	Recombinant Human Melanoma Inhibitory Activity Protein/MIA (C-6His)	10ug	882.00	立即咨询
abs04307	Recombinant Human Melanoma Inhibitory Activity Protein/MIA (C-6His)	50ug	2646.00	立即咨询
abs04307	Recombinant Human Melanoma Inhibitory Activity Protein/MIA (C-6His)	500ug	12936.00	立即咨询
abs04307	Recombinant Human Melanoma Inhibitory Activity Protein/MIA (C-6His)	1mg	17600.00	立即咨询

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Recombinant Human Melanoma Inhibitory Activity Protein/MIA (C-6His), 人蛋白Melanoma Inhibitory Activity Protein/MIA (C-6His)由爱必信(上海)生物科技有限公司为您提供，货号abs04307，规格：10ug，CAS号：，如您想了解更多关于Recombinant Human Melanoma Inhibitory Activity Protein/MIA (C-6His), 人蛋白Melanoma Inhibitory Activity Protein/MIA (C-6His)价格、Recombinant Human Melanoma Inhibitory Activity Protein/MIA (C-6His), 人蛋白Melanoma Inhibitory Activity Protein/MIA (C-6His)结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Human Melanoma Inhibitory Activity Protein/MIA (C-6His), 人蛋白Melanoma Inhibitory Activity Protein/MIA (C-6His)外，还可为您提供其他等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，爱必信客户服务电话，售前、售后均可联系。

供货周期：	一周
品牌：	爱必信
规格：	10ug
货号：	abs04307
CAS号：