Recombinant Human Ubiquitin-Conjugating Enzyme E2 K/UBE2K (N-GST), 人蛋白Ubiquitin-Conjugating Enzyme E2 K/UBE2K (N-GST)

Recombinant Human Ubiquitin-Conjugating Enzyme E2 K/UBE2K (N-GST), 人蛋白Ubiquitin-Conjugating Enzyme E2 K/UBE2K (N-GST)

参考价:¥252
供货周期: 一周
品牌: 爱必信
规格: 10ug
货号: abs04313
CAS号:
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产品描述:

产品名称:Recombinant Human Ubiquitin-Conjugating Enzyme E2 K/UBE2K (N-GST)

背景说明: Ubiquitin-Conjugating Enzyme E2 K (UBE2K) belongs to the E2 Ubiquitin-Conjugating Enzyme family. UBE2K is highly expressed in the brain, with highest levels found in cortex and striatum, and at lower levels in cerebellum and brainstem. UBE2K may mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. UBE2K is associated with the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. In addition, UBE2K is involved in Alzheimer's disease, Huntington's disease and antigen processing through its interaction with huntingtin, and MHC-heavy chain proteins.

描述: Recombinant Human Ubiquitin-Conjugating Enzyme E2 K is produced by our E.coli expression system and the target gene encoding Met1-Asn200 is expressed with a GST tag at the N-terminus.

氨基酸序列: MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKL TQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEML KMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKS SKYIAWPLQGWQATFGGGDHPPKSDLVPRGSMANIAVQRIKREFKEVLKSEETSKNQIKVDLVDE NFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQ WAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTK KIENLCAMGFDRNAVIVALSSKSWDVETATELLLSN

别名: Ubiquitin-Conjugating Enzyme E2 K, Huntingtin-Interacting Protein 2, HIP-2, Ubiquitin Carrier Protein, Ubiquitin-Conjugating Enzyme E2-25 kDa, Ubiquitin-Conjugating Enzyme E2(25K), Ubiquitin-Conjugating Enzyme E2-25K, Ubiquitin-Protein Ligase, UBE2K, HIP2, LIG

Accession: P61086

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Escherichia coli.

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.

储存/保存方法: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs04313   Recombinant Human Ubiquitin-Conjugating Enzyme E2 K/UBE2K (N-GST)   10ug   252.00   立即咨询
  abs04313   Recombinant Human Ubiquitin-Conjugating Enzyme E2 K/UBE2K (N-GST)   50ug   630.00   立即咨询
  abs04313   Recombinant Human Ubiquitin-Conjugating Enzyme E2 K/UBE2K (N-GST)   500ug   5292.00   立即咨询
  abs04313   Recombinant Human Ubiquitin-Conjugating Enzyme E2 K/UBE2K (N-GST)   1mg   7200.00   立即咨询

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