Recombinant Human β-2-Microglobulin/B2M (C-6His), 人蛋白β-2-Microglobulin/B2M (C-6His)|10ug|abs04343-爱必信(上海)生物科技有限公司

产品详情

公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!

产品描述：

产品名称：Recombinant Human β-2-Microglobulin/B2M (C-6His)

描述:

Recombinant Human beta-2-Microglobulin is produced by our Mammalian expression system and the target gene encoding Ile21-Met119 is expressed with a 6His tag at the C-terminus.

氨基酸序列: IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLL YYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDMVDHHHHHH

背景说明: β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major histocompatibility complex (MHC) class I molecules, involved in the presentation of peptide antigens to the immune system. Polymers of beta 2-microglobulin can be found in tissues from patients on long-term hemodialysis. B2M is a protein found on the surface of many cells and plentiful on the surface of white blood cells. Serum B2M concentration is increased in renal diseases, various malignant diseases and some inflammatory and autoimmune disorders. B2M may adopt the fibrillar configuration of amyloid in certain pathologic states. The capacity to assemble into amyloid fibrils is concentration dependent. B2M has been shown as a marker for monitoring inflammatory disease activity and it appears likely to have a destructive role in amyloidosis-related arthritis. B2M might be involved in the OA (osteoarthritis) pathogenesis. Defects in B2M are the cause of hypercatabolic hypoproteinemia. Affected individuals show marked reduction in serum concentrations of immunoglobulin and albumin, probably due to rapid degradation. B2M could be a potential therapeutic target in ovarian cancer.

别名: Beta-2-Microglobulin, B2M

Accession: P61769

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

形态: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

储存/保存方法: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04343	Recombinant Human β-2-Microglobulin/B2M (C-6His)	10ug	882.00	立即咨询
abs04343	Recombinant Human β-2-Microglobulin/B2M (C-6His)	50ug	2646.00	立即咨询
abs04343	Recombinant Human β-2-Microglobulin/B2M (C-6His)	500ug	12936.00	立即咨询
abs04343	Recombinant Human β-2-Microglobulin/B2M (C-6His)	1mg	17600.00	立即咨询

产品更多信息请进入爱必信网站咨询

供货周期：	一周
品牌：	爱必信
规格：	10ug
货号：	abs04343
CAS号：