Recombinant Rat C-C Motif Chemokine 5/CCL5 (N-6His), 大鼠蛋白C-C Motif Chemokine 5/CCL5 (N-6His)|10ug|abs04407-爱必信(上海)生物科技有限公司

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产品名称：Recombinant Rat C-C Motif Chemokine 5/CCL5 (N-6His)

描述: Recombinant Rat C-C motif chemokine 5 is produced by our E.coli expression system and the target gene encoding Ser25-Ser92 is expressed with a 6His tag at the N-terminus.

氨基酸序列: MNHKVHHHHHHMDDDDKSPYGSDTTPCCFAYLSLALPRAHVKEYFYTSSKCSNLAVVFVTRRNRQ VCANPEKKWVQEYINYLEMS

背景说明: C-C motif chemokine 5(CCL5) is a β-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. CCL5 is secreted by many cell types at inflammatory sites, and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. Inflammatory responses can be impaired by the sequestration of CCL5 by the cytomegalovirus protein US28. Oligomerization of CCL5 on glycosaminoglycans is required for CCR1mediated leukocyte adhesion and activation as well as CCL5’s interaction with the chemokine CXCL4/PF4.The deposition of CCL5 on activated vascular endothelial cells is crucial for monocyte adhesion to damaged vasculature, but CCL5 oligomerization is not required for the extravasation of adherent leukocytes.CCL5 is upregulated in breast cancer and promotes tumor progression through the attraction of proinflammatory macrophages in addition to its actions on tumor cells, stromal cells, and the vasculature.

别名: C-C motif chemokine 5; SIS-delta; Small-inducible cytokine A5; T-cell-specific protein RANTES; Ccl5; Scya5

Accession: P50231

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Escherichia coli.

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

形态: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, 2mM EDTA, pH7.4.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04407	Recombinant Rat C-C Motif Chemokine 5/CCL5 (N-6His)	10ug	756.00	立即咨询
abs04407	Recombinant Rat C-C Motif Chemokine 5/CCL5 (N-6His)	50ug	2100.00	立即咨询
abs04407	Recombinant Rat C-C Motif Chemokine 5/CCL5 (N-6His)	500ug	9408.00	立即咨询
abs04407	Recombinant Rat C-C Motif Chemokine 5/CCL5 (N-6His)	1mg	12800.00	立即咨询

产品更多信息请进入爱必信网站咨询

Recombinant Rat C-C Motif Chemokine 5/CCL5 (N-6His), 大鼠蛋白C-C Motif Chemokine 5/CCL5 (N-6His)由爱必信(上海)生物科技有限公司为您提供，货号abs04407，规格：10ug，CAS号：，如您想了解更多关于Recombinant Rat C-C Motif Chemokine 5/CCL5 (N-6His), 大鼠蛋白C-C Motif Chemokine 5/CCL5 (N-6His)价格、Recombinant Rat C-C Motif Chemokine 5/CCL5 (N-6His), 大鼠蛋白C-C Motif Chemokine 5/CCL5 (N-6His)结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Rat C-C Motif Chemokine 5/CCL5 (N-6His), 大鼠蛋白C-C Motif Chemokine 5/CCL5 (N-6His)外，还可为您提供其他等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，爱必信客户服务电话，售前、售后均可联系。

供货周期：	一周
品牌：	爱必信
规格：	10ug
货号：	abs04407
CAS号：