Recombinant Human Ubiquitin-Like Protein ISG15/ISG15 (C-6His), 人蛋白Ubiquitin-Like Protein ISG15/ISG15 (C-6His)|10ug|abs04420-爱必信(上海)生物科技有限公司

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产品描述：

产品名称：Recombinant Human Ubiquitin-Like Protein ISG15/ISG15 (C-6His)

描述: Recombinant Human Interferon-stimulated Gene 15 is produced by our E.coli expression system and the target gene encoding Gly2-Gly157 is expressed with a 6His tag at the C-terminus.

氨基酸序列: GWDLTVKMLAGNEFQVSLSSSMSVSELKAQITQKIGVHAFQQRLAVHPSGVALQDRVPLASQGLG PGSTVLLVVDKCDEPLNILVRNNKGRSSTYEVRLTQTVAHLKQQVSGLEGVQDDLFWLTFEGKPL EDQLPLGEYGLKPLSTVFMNLRLRGGLEHHHHHH

背景说明: Ubiquitin-Like Protein ISG15 (ISG15) is a ubiquitin-like protein that becomes conjugated to many cellular proteins upon activation by interferon-alpha and -beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermediate filaments, this protein is sometimes secreted. ISG15 becomes conjugated to a diverse set of proteins after IFN-alpha/beta stimulation or microbial challenge. The functions or biochemical consequences ISG15 conjugation to proteins are not yet known, but it appears that this modification does not target proteins for proteasomal degradation. ISG15 shows specific chemotactic activity towards neutrophils and activates them to induce release of eosinophil chemotactic factors. Upon interferon treatment, ISG15 can be detected in both free and conjugated forms, and is secreted from monocytes and lymphocytes where it can function as a cytokine. In the cell, ISG15 co-localizes with intermediate filaments and ISGylation may modulate the JAK-STAT pathway or certain aspects of neurological disease.

别名: Ubiquitin-Like Protein ISG15, Interferon-Induced 15 kDa Protein, Interferon-Induced 17 kDa Protein, IP17, Ubiquitin Cross-Reactive Protein, hUCRP, ISG15, G1P2, UCRP

Accession: P05161

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Escherichia coli.

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Supplied as a 0.2 μm filtered solution of 50mM HEPES, 100mM NaCl, pH 8.0.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04420	Recombinant Human Ubiquitin-Like Protein ISG15/ISG15 (C-6His)	10ug	378.00	立即咨询
abs04420	Recombinant Human Ubiquitin-Like Protein ISG15/ISG15 (C-6His)	50ug	882.00	立即咨询
abs04420	Recombinant Human Ubiquitin-Like Protein ISG15/ISG15 (C-6His)	500ug	9408.00	立即咨询
abs04420	Recombinant Human Ubiquitin-Like Protein ISG15/ISG15 (C-6His)	1mg	12800.00	立即咨询

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Recombinant Human Ubiquitin-Like Protein ISG15/ISG15 (C-6His), 人蛋白Ubiquitin-Like Protein ISG15/ISG15 (C-6His)由爱必信(上海)生物科技有限公司为您提供，货号abs04420，规格：10ug，CAS号：，如您想了解更多关于Recombinant Human Ubiquitin-Like Protein ISG15/ISG15 (C-6His), 人蛋白Ubiquitin-Like Protein ISG15/ISG15 (C-6His)价格、Recombinant Human Ubiquitin-Like Protein ISG15/ISG15 (C-6His), 人蛋白Ubiquitin-Like Protein ISG15/ISG15 (C-6His)结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Human Ubiquitin-Like Protein ISG15/ISG15 (C-6His), 人蛋白Ubiquitin-Like Protein ISG15/ISG15 (C-6His)外，还可为您提供其他等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，爱必信客户服务电话，售前、售后均可联系。

供货周期：	一周
品牌：	爱必信
规格：	10ug
货号：	abs04420
CAS号：