Recombinant Human NEDD8-Conjugating Enzyme UBC12/UBE2M, 人蛋白NEDD8-Conjugating Enzyme UBC12/UBE2M|10ug|abs04422-爱必信(上海)生物科技有限公司

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产品描述：

产品名称：Recombinant Human NEDD8-Conjugating Enzyme UBC12/UBE2M

描述: Recombinant Human Ubiquitin-conjugating Enzyme E2M is produced by our E.coli expression system and the target gene encoding Met1-Lys183 is expressed.

氨基酸序列: MIKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDISFSDPDDLLNFKLVIC PDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIY GLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFERCLK

背景说明: UBE2M is a member of the E2 ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. UBE2M accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. It involved in cell proliferation and is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation.

别名: NEDD8-conjugating enzyme Ubc12, NEDD8 carrier protein, NEDD8 protein ligase, Ubiquitin-conjugating enzyme E2 M, UBC12, UBE2M,

Accession: P61081

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Escherichia coli.

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Supplied as a 0.2 μm filtered solution of 50mM HEPES,pH 7.5,2mM DTT,150mM NaCl,10%glycerol .

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04422	Recombinant Human NEDD8-Conjugating Enzyme UBC12/UBE2M	10ug	252.00	立即咨询
abs04422	Recombinant Human NEDD8-Conjugating Enzyme UBC12/UBE2M	50ug	756.00	立即咨询
abs04422	Recombinant Human NEDD8-Conjugating Enzyme UBC12/UBE2M	500ug	5040.00	立即咨询
abs04422	Recombinant Human NEDD8-Conjugating Enzyme UBC12/UBE2M	1mg	7600.00	立即咨询

产品更多信息请进入爱必信网站咨询

Recombinant Human NEDD8-Conjugating Enzyme UBC12/UBE2M, 人蛋白NEDD8-Conjugating Enzyme UBC12/UBE2M由爱必信(上海)生物科技有限公司为您提供，货号abs04422，规格：10ug，CAS号：，如您想了解更多关于Recombinant Human NEDD8-Conjugating Enzyme UBC12/UBE2M, 人蛋白NEDD8-Conjugating Enzyme UBC12/UBE2M价格、Recombinant Human NEDD8-Conjugating Enzyme UBC12/UBE2M, 人蛋白NEDD8-Conjugating Enzyme UBC12/UBE2M结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Human NEDD8-Conjugating Enzyme UBC12/UBE2M, 人蛋白NEDD8-Conjugating Enzyme UBC12/UBE2M外，还可为您提供其他等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，爱必信客户服务电话，售前、售后均可联系。

供货周期：	一周
品牌：	爱必信
规格：	10ug
货号：	abs04422
CAS号：