Recombinant Human Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His), 人蛋白Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His)|10ug|abs04446-爱必信(上海)生物科技有限公司

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产品描述：

产品名称：Recombinant Human Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His)

描述: Recombinant Human EGFR is produced by our Mammalian expression system and the target gene encoding Leu25-Ser645 is expressed with a 6His tag at the C-terminus.

氨基酸序列: LEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYV LIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNP ALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQC SGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGK YSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSL SINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENR TDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKK LFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEG EPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWK YADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSVDHHHHHH

背景说明: The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human EGFR subfamily. All these family members are type I transmembrane glycoproteins with an extracellular ligand binding domain. The extracellular ligand binding domain is containing two cysteine-rich domains separated by a spacer region and a cytoplasmic domain containing a membrane-proximal tyrosine kinase domain. Ligand binding could induce EGFR homodimerization and heterodimerization with ErbB2, resulting in cell signaling, heterodimerization tyrosine phosphorylation and kinase activation. It can bind EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, HB-EGF, epigen, and so on. Its signaling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis. EGFR can also be recruited to form heterodimers with the ligand-activated ErbB3 or ErbB4. EGFR is overexpressed in different tumors. Several anti-cancer drugs use EGFR as target.

别名: Epidermal growth factor receptor,Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1, EGFR,ERBB, ERBB1, HER1

Accession: P00533

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

形态: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04446	Recombinant Human Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His)	10ug	1260.00	立即咨询
abs04446	Recombinant Human Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His)	50ug	3696.00	立即咨询
abs04446	Recombinant Human Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His)	500ug	12936.00	立即咨询
abs04446	Recombinant Human Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His)	1mg	19200.00	立即咨询

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Recombinant Human Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His), 人蛋白Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His)由爱必信(上海)生物科技有限公司为您提供，货号abs04446，规格：10ug，CAS号：，如您想了解更多关于Recombinant Human Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His), 人蛋白Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His)价格、Recombinant Human Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His), 人蛋白Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His)结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Human Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His), 人蛋白Epidermal Growth Factor Receptor/EGFR/ErbB1/HER1 (C-6His)外，还可为您提供其他等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，爱必信客户服务电话，售前、售后均可联系。

供货周期：	一周
品牌：	爱必信
规格：	10ug
货号：	abs04446
CAS号：