供货周期: | 一周 |
品牌: | 爱必信 |
规格: | 10ug |
货号: | abs04448 |
CAS号: |
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产品描述: 产品名称:Recombinant Human Interferon γ Receptor 1/IFNGR1 (C-6His) 描述: Recombinant Human Interferon gamma receptor 1 is produced by our Mammalian expression system and the target gene encoding Glu18-Ser245 is expressed with a 6His tag at the C-terminus. 氨基酸序列: EMGTADLGPSSVPTPTNVTIESYNMNPIVYWEYQIMPQVPVFTVEVKNYGVKNSEWIDACINISH HYCNISDHVGDPSNSLWVRVKARVGQKESAYAKSEEFAVCRDGKIGPPKLDIRKEEKQIMIDIFH PSVFVNGDEQEVDYDPETTCYIRVYNVYVRMNGSEIQYKILTQKEDDCDEIQCQLAIPVSSLNSQ YCVSAEGVLHVWGVTTEKSKEVCITIFNSSIKGVDHHHHHH 背景说明: Interferon gamma receptor 1(IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. 别名: Interferon gamma receptor 1,IFNGR1,CDw119,CD119 Accession: P15260 纯度: Greater than 95% as determined by reducing SDS-PAGE. 来源: Human Cells 内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. 形态: Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
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