Recombinant Mouse PD-L1/B7-H1/CD274 (C-6His), 小鼠蛋白PD-L1/B7-H1/CD274 (C-6His)|10ug|abs04460-爱必信(上海)生物科技有限公司

产品详情

公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!

产品描述：

产品名称：Recombinant Mouse PD-L1/B7-H1/CD274 (C-6His)

描述:

Recombinant Mouse Programmed Cell Death 1 Ligand 1 is produced by our Mammalian expression system and the target gene encoding Phe19-Thr238 is expressed with a 6His tag at the C-terminus.

氨基酸序列: FTITAPKDLYVVEYGSNVTMECRFPVERELDLLALVVYWEKEDEQVIQFVAGEEDLKPQHSNFRG RASLPKDQLLKGNAALQITDVKLQDAGVYCCIISYGGADYKRITLKVNAPYRKINQRISVDPATS EHELICQAEGYPEAEVIWTNSDHQPVSGKRSVTTSRTEGMLLNVTSSLRVNATANDVFYCTFWRS QPGQNHTAELIIPELPATHPPQNRTVDHHHHHH

背景说明: Mouse Programmed cell death 1 ligand 1(Cd274，PD-L1), is a member of the growing B7 family of immune proteins.It involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.B7-H1 has been identified as one of two ligands for programmed death1 (PD1), a member of the CD28 family of immunoreceptors. B7-H1 is constitutively expressed in several organs such as heart, skeletal muscle B7-H1 expression is upregulated in a small fraction of activated T and B cells and a much larger fraction of activated monocytes. The costimulatory function of B7-H1 is critical for enhancing maturation and differentiation of T-cells in lymphoid organs.B7-H1 expression is also induced in dendritic cells and keratinocytes after IFN gamma stimulation. Interaction of B7-H1 with PD1 results in inhibition of TCR-mediated proliferation and cytokine production. The B7-H1:PD1 pathway is involved in the negative regulation of some immune responses and may play an important role in the regulation of peripheral tolerance.

别名: Programmed cell death 1 ligand 1Cd274, programmed cell death 1 ligand 1,PD-L1,PDCD1 ligand 1,programmed death ligand 1,B7 homolog 1,B7-H1,CD274

Accession: Q9EP73

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

形态: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

储存/保存方法: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04460	Recombinant Mouse PD-L1/B7-H1/CD274 (C-6His)	10ug	420.00	立即咨询
abs04460	Recombinant Mouse PD-L1/B7-H1/CD274 (C-6His)	50ug	882.00	立即咨询
abs04460	Recombinant Mouse PD-L1/B7-H1/CD274 (C-6His)	500ug	5460.00	立即咨询
abs04460	Recombinant Mouse PD-L1/B7-H1/CD274 (C-6His)	1mg	8400.00	立即咨询

产品更多信息请进入爱必信网站咨询

供货周期：	一周
品牌：	爱必信
规格：	10ug
货号：	abs04460
CAS号：