Recombinant Human Thymic Stromal Lymphopoietin/TSLP, 人蛋白Thymic Stromal Lymphopoietin/TSLP|10ug|abs04470-爱必信(上海)生物科技有限公司

Recombinant Human Thymic Stromal Lymphopoietin/TSLP, 人蛋白Thymic Stromal Lymphopoietin/TSLP

参考价：¥1260

供货周期：

一周

品牌：

爱必信

规格：

10ug

货号：

abs04470

CAS号：

产品详情

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产品描述：

产品名称：Recombinant Human Thymic Stromal Lymphopoietin/TSLP

描述: Recombinant Human Thymic stromal lymphopoietin is produced by our E.coli expression system and the target gene encoding Tyr29-Gln159 is expressed.

氨基酸序列: YDFTNCDFEKIKAAYLSTISKDLITYMSGTKSTEFNNTVSCSNRPHCLTEIQSLTFNPTAGCASL AKEMFAMKTKAALAIWCPGYSETQINATQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNRPLLKQ Q

背景说明: Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP (159 aa) and sfTSLP (63 aa) produced by alternative splicing . lfTSLP (159aa) is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral mucosa, skin and in salivary glands. In aa sequence level, Human TSLP displays about 43% identity with mouse TSLP. Thymic stromal lymphopoietin (TSLP) is a cytokine that functions mainly on myeloid cells; it induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells . TSLP has proliferative effects on the myeloid cell line and may initiate asthma or atopic dermatitis responses by directly activating mast cells . TSLP signals cells via the interleukin-7 receptor-α chain (IL-7Rα), shared with IL-7, together with the TSLP receptor (TSLPR) subunit. Recent studies indicate that TSLP and its receptor are novel therapeutic targets for rheumatoid arthritis , for increased intraarticular TSLP concentrations in patients has caused chemotaxis and activation of arthritogenic T cells.

别名: Thymic stromal lymphopoietin/TSLP

Accession: Q969D9

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Escherichia coli.

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

形态: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04470	Recombinant Human Thymic Stromal Lymphopoietin/TSLP	10ug	1260.00	立即咨询
abs04470	Recombinant Human Thymic Stromal Lymphopoietin/TSLP	50ug	3696.00	立即咨询
abs04470	Recombinant Human Thymic Stromal Lymphopoietin/TSLP	500ug	12936.00	立即咨询
abs04470	Recombinant Human Thymic Stromal Lymphopoietin/TSLP	1mg	17600.00	立即咨询

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