供货周期: | 一周 |
品牌: | 爱必信 |
规格: | 10ug |
货号: | abs04471 |
CAS号: |
公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)!
产品描述: 产品名称:Recombinant Mouse IL-1 Receptor Antagonist Protein/IL-1ra/IL-1RA 描述: Recombinant Mouse Interleukin-1 Receptor Antagonist Protein is produced by our E.coli expression system and the target gene encoding Arg27-Gln178 is expressed. 氨基酸序列: MRPSGKRPCKMQAFRIWDTNQKTFYLRNNQLIAGYLQGPNIKLEEKIDMVPIDLHSVFLGIHGGK LCLSCAKSGDDIKLQLEEVNITDLSKNKEEDKRFTFIRSEKGPTTSFESAACPGWFLCTTLEADR PVSLTNTPEEPLIVTKFYFQEDQ 背景说明: Interleukin-1 receptor antagonist protein (Il1rn), also known as IL-1ra, IRAP or IL1 inhibitor, is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1 alpha (IL1A) and interleukin 1 beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. The mouse Il1rn gene encodes a 178 amino acids (aa) protein with a 26 aa signal peptide. Mouse Il1rn protein shares 26% and 19% identity with its homologues IL-1 beta and IL-1 alpha, respectively. Il1rn can Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling, but has no interleukin-1 like activity. Recently, an recombinant human Il1rn protein is used in the treatment of rheumatoid arthritis, an autoimmune disease in which IL-1 plays a key role. 别名: IL-1RN/IL-1ra/IRAP/IL1 inhibitor/Il1rn Accession: P25085 纯度: Greater than 95% as determined by reducing SDS-PAGE. 来源: Escherichia coli. 内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. 溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 形态: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
产品信息订购:
|
相关产品
Recombinant 2019-nCoV S-trimer Protein (C-6His)
2500
Recombinant 2019-nCoV S protein RBD Protein (C-mFc)
1700
Recombinant 2019-nCoV S Protein RBD-SD1 (C-6His)
1700
Recombinant 2019-nCoV S Protein RBD-SD1 (C-mFC)
1700
Recombinant 2019-nCoV S2 Protein (C-Fc)
1700
Recombinant 2019-nCoV S1 Protein (C-Fc)
1700
Recombinant 2019-nCoV S Protein RBD (C-6His)
1700
Recombinant Human PD-1/PDCD1/CD279, 人蛋白PD-1/PDCD1/CD279
798
详细地址
关注
拨打电话
留言咨询