Recombinant Mouse Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His), 小鼠蛋白Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His)|10ug|abs04480-爱必信(上海)生物科技有限公司

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产品描述：

产品名称：Recombinant Mouse Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His)

描述: Recombinant Mouse LAG-3 is produced by our Mammalian expression system and the target gene encoding Ser23-Leu442 is expressed with a 6His tag at the C-terminus.

氨基酸序列: SGPGKELPVVWAQEGAPVHLPCSLKSPNLDPNFLRRGGVIWQHQPDSGQPTPIPALDLHQGMPSP RQPAPGRYTVLSVAPGGLRSGRQPLHPHVQLEERGLQRGDFSLWLRPALRTDAGEYHATVRLPNR ALSCSLRLRVGQASMIASPSGVLKLSDWVLLNCSFSRPDRPVSVHWFQGQNRVPVYNSPRHFLAE TFLLLPQVSPLDSGTWGCVLTYRDGFNVSITYNLKVLGLEPVAPLTVYAAEGSRVELPCHLPPGV GTPSLLIAKWTPPGGGPELPVAGKSGNFTLHLEAVGLAQAGTYTCSIHLQGQQLNATVTLAVITV TPKSFGLPGSRGKLLCEVTPASGKERFVWRPLNNLSRSCPGPVLEIQEARLLAERWQCQLYEGQR LLGATVYAAESSSGAHSARRISGDLKGGHLHHHHHH

背景说明: Lymphocyte-activation gene 3 (LAG3), also known as CD223, is a type I transmembrane protein with four extracellular Ig-like domains, designated D1 to D4 and belongs to the immunoglobulin superfamily. The gene for LAG3 lies adjacent to the gene for CD4 on human chromosome 12p13.32 and shares approximately 20% identical to the CD4 gene. LAG3 is expressed on activated T cells, natural killer cells, B cells and plasmacytoid dendritic cells. LAG3 binds with high affinity to MHC class II molecules, and it interferes competitively with the binding of CD4 to MHC class II and thereby blocks the transduction of stimulatory signals mediated by this interaction. LAG3 negatively regulates cellular proliferation, activation, and homeostasis of T cells, and plays an important role in Treg suppressive function. LAG3 is the target of various drug development programs to develop new treatments for cancer and autoimmune disorders. The soluble form, sLAG-3, is being developed as a cancer drug.

别名: Lymphocyte activation gene 3 protein,CD223,Lag3, REF: C1128

Accession: Q61790

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04480	Recombinant Mouse Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His)	10ug	1260.00	立即咨询
abs04480	Recombinant Mouse Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His)	50ug	3696.00	立即咨询
abs04480	Recombinant Mouse Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His)	500ug	12936.00	立即咨询
abs04480	Recombinant Mouse Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His)	1mg	17600.00	立即咨询

产品更多信息请进入爱必信网站咨询

Recombinant Mouse Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His), 小鼠蛋白Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His)由爱必信(上海)生物科技有限公司为您提供，货号abs04480，规格：10ug，CAS号：，如您想了解更多关于Recombinant Mouse Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His), 小鼠蛋白Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His)价格、Recombinant Mouse Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His), 小鼠蛋白Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His)结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Mouse Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His), 小鼠蛋白Lymphocyte Activation Gene 3/LAG-3/CD223 (C-6His)外，还可为您提供其他等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，爱必信客户服务电话，售前、售后均可联系。

供货周期：	一周
品牌：	爱必信
规格：	10ug
货号：	abs04480
CAS号：