Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His), Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His)|10ug|abs04527-爱必信(上海)生物科技有限公司

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产品描述：

产品名称：Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His)

描述: Recombinant Cynomolgus monkey Programmed Cell Death Protein 1 is produced by our Mammalian expression system and the target gene encoding Pro21-Gln167 is expressed with a 6His tag at the C-terminus.

氨基酸序列: PGWFLESPDRPWNAPTFSPALLLVTEGDNATFTCSFSNASESFVLNWYRMSPSNQTDKLAAFPED RSQPGQDCRFRVTRLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESLRAELRVTERRAE VPTAHPSPSPRPAGQFQHHHHHH

背景说明: Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PDCD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PDCD1 has been suggested to be involved in lymphocyte clonal selection and peripheral tolerance, and thus contributes to the prevention of autoimmune diseases. As a cell surface molecule, PDCD1 regulates the adaptive immune response. Engagement of PD-1 by its ligands PD-L1 or PD-L2 transduces a signal that inhibits T-cell proliferation, cytokine production, and cytolytic function.

别名: Programmed cell death 1, PD-1, PD1

Accession: B0LAJ3

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04527	Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His)	10ug	798.00	立即咨询
abs04527	Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His)	50ug	2100.00	立即咨询
abs04527	Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His)	500ug	12936.00	立即咨询
abs04527	Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His)	1mg	17600.00	立即咨询

产品更多信息请进入爱必信网站咨询

Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His), Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His)由爱必信(上海)生物科技有限公司为您提供，货号abs04527，规格：10ug，CAS号：，如您想了解更多关于Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His), Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His)价格、Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His), Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His)结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His), Recombinant Cynomolgus PDCD1/PD-1/CD279 (C-6His)外，还可为您提供其他等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，爱必信客户服务电话，售前、售后均可联系。

供货周期：	一周
品牌：	爱必信
规格：	10ug
货号：	abs04527
CAS号：