Recombinant Mouse Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His), 小鼠蛋白Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)

Recombinant Mouse Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His), 小鼠蛋白Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)

参考价:¥1260
供货周期: 一周
品牌: 爱必信
规格: 10ug
货号: abs04531
CAS号:
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产品描述:

产品名称:Recombinant Mouse Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)

描述: Recombinant Mouse Indoleamine 2,3-dioxygenase is produced by our E.coli expression system and the target gene encoding Met1-Pro407 is expressed with a 6His tag at the N-terminus.

氨基酸序列: MNHKVHHHHHHMALSKISPTEGSRRILEDHHIDEDVGFALPHPLVELPDAYSPWVLVARNLPVLI ENGQLREEVEKLPTLSTDGLRGHRLQRLAHLALGYITMAYVWNRGDDDVRKVLPRNIAVPYCELS EKLGLPPILSYADCVLANWKKKDPNGPMTYENMDILFSFPGGDCDKGFFLVSLLVEIAASPAIKA IPTVSSAVERQDLKALEKALHDIATSLEKAKEIFKRMRDFVDPDTFFHVLRIYLSGWKCSSKLPE GLLYEGVWDTPKMFSGGSAGQSSIFQSLDVLLGIKHEAGKESPAEFLQEMREYMPPAHRNFLFFL ESAPPVREFVISRHNEDLTKAYNECVNGLVSVRKFHLAIVDTYIMKPSKKKPTDGDKSEEPSNVE SRGTGGTNPMTFLRSVKDTTEKALLSWP

背景说明: Indoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. This protein is normally expressed in the dendritic cells, macrophages, microglia, eosinophils, fibroblasts, endothelial cells, and most tumor cells. IDO activity is associated with immunosuppression and immune attenuation. Several studies showed that IDO can contribute to immune escape when expressed directly in tumor cells or when expressed in immunosuppressive antigen presenting cells such as tolerogenic dendritic cells or tumor associated macrophages. IDO also is a promising therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression.

别名: Indole 2,3-dioxygenase, Indoleamine 2,3-dioxygenase 1, IDO-1, IDO1, IDO, INDO

Accession: P28776

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Escherichia coli.

内毒素水平: Less than 0.1 ng/?g (1 IEU/?g) as determined by LAL test.

形态: Supplied as a 0.2 μm filtered solution of 20mM Sodium Acetate, 150mM NaCl and 20% Glycerol, pH4.5..

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs04531   Recombinant Mouse Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)   10ug   1260.00   立即咨询
  abs04531   Recombinant Mouse Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)   50ug   3696.00   立即咨询
  abs04531   Recombinant Mouse Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)   500ug   14112.00   立即咨询
  abs04531   Recombinant Mouse Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)   1mg   19200.00   立即咨询

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Recombinant Mouse Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His), 小鼠蛋白Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)由爱必信(上海)生物科技有限公司为您提供,货号abs04531,规格:10ug,CAS号:,如您想了解更多关于Recombinant Mouse Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His), 小鼠蛋白Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)价格、Recombinant Mouse Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His), 小鼠蛋白Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)结构式、批发、用途等信息,欢迎咨询。除供应Recombinant Mouse Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His), 小鼠蛋白Indoleamine 2,3-Dioxygenase/IDO/INDO (N-6His)外,还可为您提供其他等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,爱必信客户服务电话,售前、售后均可联系。
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