Recombinant Mouse IL-1 Receptor Type 2/IL-1 RII (C-6His), 小鼠蛋白IL-1 Receptor Type 2/IL-1 RII (C-6His)|10ug|abs04544-爱必信(上海)生物科技有限公司

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产品描述：

产品名称：Recombinant Mouse IL-1 Receptor Type 2/IL-1 RII (C-6His)

描述: Recombinant Mousen Il1r2 protein/IL-1 RII is produced by our Mammalian expression system and the target gene encoding Phe14-Glu355 is expressed fused with a 6His tag at the C-terminus.

氨基酸序列: FTTPTVVHTGKVSESPITSEKPTVHGDNCQFRGREFKSELRLEGEPVVLRCPLAPHSDISSSSHS FLTWSKLDSSQLIPRDEPRMWVKGNILWILPAVQQDSGTYICTFRNASHCEQMSVELKVFKNTEA SLPHVSYLQISALSTTGLLVCPDLKEFISSNADGKIQWYKGAILLDKGNKEFLSAGDPTRLLISN TSMDDAGYYRCVMTFTYNGQEYNITRNIELRVKGTTTEPIPVIISPLETIPASLGSRLIVPCKVF LGTGTSSNTIVWWLANSTFISAAYPRGRVTEGLHHQYSENDENYVEVSLIFDPVTREDLHTDFKC VASNPRSSQSLHTTVKEHHHHHH

背景说明: Mouse Interleukin 1 receptor, type II (IL1R2) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL-1R2 structurally consisting of a ligand binding portion comprised of three Ig-like domains, a single transmembrane region, and a short cytoplasmic domain. It is expressed in a variety of cell types including B lymphocytes, neutrophils, monocytes, large granular leukocytes and endothelial cells. Mouse IL1RII shares 59% amino acid sequence homology with human IL1 RII in their extracellular domains. The pleiotropic cytokine IL1 is produced to regulate development and maintenance of the inflammatory responses, and binds to specific plasma membrane receptors on cells. Two distinct types of IL1 receptors which are able to bind IL1 specifically have been identified, designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1R1 contributes to IL-1 signaling, whereas the IL-1R2 has no signaling property and acts as a decoy for IL-1.

别名: Interleukin-1 receptor type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 antigen-like family member B, CD121b, IL-1 type II receptor, Interleukin-1 receptor beta, IL-1R-beta, Interleukin-1 receptor type II, CD121b

Accession: P27931

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04544	Recombinant Mouse IL-1 Receptor Type 2/IL-1 RII (C-6His)	10ug	798.00	立即咨询
abs04544	Recombinant Mouse IL-1 Receptor Type 2/IL-1 RII (C-6His)	50ug	2100.00	立即咨询
abs04544	Recombinant Mouse IL-1 Receptor Type 2/IL-1 RII (C-6His)	500ug	12936.00	立即咨询
abs04544	Recombinant Mouse IL-1 Receptor Type 2/IL-1 RII (C-6His)	1mg	17600.00	立即咨询

产品更多信息请进入爱必信网站咨询

供货周期：	一周
品牌：	爱必信
规格：	10ug
货号：	abs04544
CAS号：