Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His), 人蛋白Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His)|10ug|abs04564-爱必信(上海)生物科技有限公司

产品详情

公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）!

产品描述：

产品名称：Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His)

描述: Recombinant Human Receptor tyrosine-protein kinase ErbB-2 is produced by our Mammalian expression system and the target gene encoding Thr23-Thr652 is expressed with a 6His tag at the C-terminus.

氨基酸序列: TQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEVQGYVLIA HNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGG VLIQRNPQLCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTR TVCAGGCARCKGPLPTDCCHEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESM PNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGM EHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYI SAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFV HTVPWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVE ECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPD LSYMPIWKFPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTHHHHHH

背景说明: Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and differentiation. HER2 has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on. HER2 is activated by dimerization and not activated by EGF, TGF-alpha and amphiregulin. Interaction with PTK6 increases its intrinsic kinase activity.It is heterodimer with EGFR, ERBB3 and ERBB4. HER2 associates with the 5'-TCAAATTC-3' sequence in the PTGS2/COX-2 promoter and activates its transcription. It implicated in transcriptional activation of CDKN1A and the function of the protein involves STAT3 and SRC. And also it involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth.

别名: Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; Proto-oncogene Neu;Tyrosine kinase-type cell surface receptor HER2; ERBB2;MLN19;NGL;TKR1

Accession: P04626

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04564	Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His)	10ug	798.00	立即咨询
abs04564	Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His)	50ug	2100.00	立即咨询
abs04564	Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His)	500ug	12936.00	立即咨询
abs04564	Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His)	1mg	17600.00	立即咨询

产品更多信息请进入爱必信网站咨询

Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His), 人蛋白Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His)由爱必信(上海)生物科技有限公司为您提供，货号abs04564，规格：10ug，CAS号：，如您想了解更多关于Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His), 人蛋白Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His)价格、Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His), 人蛋白Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His)结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His), 人蛋白Receptor Tyrosine-Protein Kinase ErbB-2/HER2 (C-6His)外，还可为您提供其他等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，爱必信客户服务电话，售前、售后均可联系。

供货周期：	一周
品牌：	爱必信
规格：	10ug
货号：	abs04564
CAS号：