Recombinant Mouse ICOS Ligand/B7-H2/CD275 (C-6His), 小鼠蛋白ICOS Ligand/B7-H2/CD275 (C-6His)|10ug|abs04571-爱必信(上海)生物科技有限公司

Recombinant Mouse ICOS Ligand/B7-H2/CD275 (C-6His), 小鼠蛋白ICOS Ligand/B7-H2/CD275 (C-6His)

参考价：¥798

供货周期：

一周

品牌：

爱必信

规格：

10ug

货号：

abs04571

CAS号：

产品详情

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产品描述：

产品名称：Recombinant Mouse ICOS Ligand/B7-H2/CD275 (C-6His)

描述: Recombinant Mouse ICOS Ligand is produced by our Mammalian expression system and the target gene encoding Glu47-Lys279 is expressed fused with a 6His tag at the C-terminus.

氨基酸序列: ETEVGAMVGSNVVLSCIDPHRRHFNLSGLYVYWQIENPEVSVTYYLPYKSPGINVDSSYKNRGHL SLDSMKQGNFSLYLKNVTPQDTQEFTCRVFMNTATELVKILEEVVRLRVAANFSTPVISTSDSSN PGQERTYTCMSKNGYPEPNLYWINTTDNSLIDTALQNNTVYLNKLGLYDVISTLRLPWTSRGDVL CCVENVALHQNITSISQAESFTGNNTKNPQETHNNELKHHHHHH

背景说明: Mouse ICOS ligand(B7-H2) is an approximately transmembrane glycoprotein in the B7 family of immune regulatory molecules. B7-H2 is expressed on antigen presenting cells such as B cells, macrophages, monocytes, and dendritic cells. It binds to ICOS on activated T cells, leading to both positive and negative effects on immune responses including its own down-regulation. The B7-H2 interaction with ICOS is costimulatory for T cell proliferation as well as the development of B cells, plasma cells, follicular helper T cells and germinal centers. B7-H2 contributes to the development of allergic asthma by enhancing Th2 biased immune responses, limiting Th17 responses, and promoting eosinophilic infiltration into the lung. Its activation of ICOS on Treg limits pulmonary inflammation and airway hyperresponsiveness, promotes the development of inhalational tolerance, and impairs antitumor immunity. In the thyroid, B7-H2 is up-regulated on thyrocytes during inflammation and promotes their proliferation and production of thryoid hormones.

别名: B7 homolog 2; B7-H2;B7-like protein Gl50; B7RP-1LICOS; CD275; CD275 antigen; ICOS ligand; ICOSL; ICOS-L;inducible T-cell co-stimulator ligand; B7RP-1; CD275; GL50; ICOSL; ICOSLG; B7H2;B7RP1

Accession: Q9JHJ8

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04571	Recombinant Mouse ICOS Ligand/B7-H2/CD275 (C-6His)	10ug	798.00	立即咨询
abs04571	Recombinant Mouse ICOS Ligand/B7-H2/CD275 (C-6His)	50ug	2100.00	立即咨询
abs04571	Recombinant Mouse ICOS Ligand/B7-H2/CD275 (C-6His)	500ug	12936.00	立即咨询
abs04571	Recombinant Mouse ICOS Ligand/B7-H2/CD275 (C-6His)	1mg	17600.00	立即咨询

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