Recombinant Rat Tumor Necrosis Factor/TNF-alpha, 大鼠蛋白Tumor Necrosis Factor/TNF-alpha|10ug|abs04633-爱必信(上海)生物科技有限公司

Recombinant Rat Tumor Necrosis Factor/TNF-alpha, 大鼠蛋白Tumor Necrosis Factor/TNF-alpha

参考价：¥882

供货周期：

7天

品牌：

爱必信

型号：

10ug

货号：

abs04633

产品详情

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产品描述：

产品名称：Recombinant Rat Tumor Necrosis Factor/TNF-alpha

背景说明: Tumor necrosis factor alpha (TNF-alpha, TNFSF2) is the prototypic ligand of the TNF superfamily. Rat TNF-alpha consisits of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 179 aa extracellular domain (ECD). Within the ECD, rat TNF-alpha shares 94% aa sequence identity with mouse. TNF-alpha is produced by a wide variety of immune, epithelial, endothelial, and tumor cells. TNF exists as a homotrimer and interacts with SPPL2B. TNF is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. TNF is a key cytokine in the development of several inflammatory disorders. It contributes to the development of type 2 diabetes throught its effects on insulin resistance and fatty acid metabolism.

描述:

Recombinant Rat Tumor Necrosis Factor is produced by our E.coli expression system and the target gene encoding Leu80-Leu235 is expressed.

氨基酸序列: MLRSSSQNSSDKPVAHVVANHQAEEQLEWLSQRANALLANGMDLKDNQLVVPADGLYLIYSQVLF KGQGCPDYVLLTHTVSRFAISYQEKVSLLSAIKSPCPKDTPEGAELKPWYEPMYLGGVFQLEKGD LLSAEVNLPKYLDITESGQVYFGVIAL

别名: Tumor Necrosis Factor; Cachectin; TNF-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; Tumor Necrosis Factor; Membrane Form; Tumor Necrosis Factor; Soluble Form; Tnf; Tnfa; Tnfsf2

Accession: P16599

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Escherichia coli.

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

储存/保存方法: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04633	Recombinant Rat Tumor Necrosis Factor/TNF-alpha	10ug	882.00	立即咨询
abs04633	Recombinant Rat Tumor Necrosis Factor/TNF-alpha	50ug	2646.00	立即咨询
abs04633	Recombinant Rat Tumor Necrosis Factor/TNF-alpha	500ug	12936.00	立即咨询
abs04633	Recombinant Rat Tumor Necrosis Factor/TNF-alpha	1mg	17600.00	立即咨询

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