Recombinant Human Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His), 人蛋白Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His)

Recombinant Human Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His), 人蛋白Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His)

参考价:¥756
供货周期: 7天
品牌: 爱必信
型号: 10ug
货号: abs04642
爱必信(上海)生物科技有限公司
银牌会员2年生产商
关注展位 全部试剂
产品详情

公告提醒:爱必信所有产品和服务仅用于科学研究不用于临床应用及其他用途提供产品和服务也不为任何个人提供产品和服务)!

 

产品描述:

产品名称:Recombinant Human Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His)

描述: Recombinant Human Natural Killer Cell Receptor 2B4 is produced by our Mammalian expression system and the target gene encoding Cys22-Arg221 is expressed with a 6His tag at the C-terminus.

氨基酸序列: CQGSADHVVSISGVPLQLQPNSIQTKVDSIAWKKLLPSQNGFHHILKWENGSLPSNTSNDRFSFI VKNLSLLIKAAQQQDSGLYCLEVTSISGKVQTATFQVFVFDKVEKPRLQGQGKILDRGRCQVALS CLVSRDGNVSYAWYRGSKLIQTAGNLTYLDEEVDINGTHTYTCNVSNPVSWESHTLNLTQDCQNA HQEFRHHHHHH

背景说明: Natural killer cell receptor 2B4 is a type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family.2B4 interacts with CD48, while other SLAM family proteins interact homophilically. Three additional splice variants of human 2B4 have deletions of the short region between the Ig-like domains, the second Ig-like domain, or a portion of the cytoplasmic tail.2B4 is expressed on all NK cells, γδ T cells, monocytes, some CD4+ and CD8+ T cells, and some dendritic cells. CD48 mediates 2B4+ cell interactions with nearly all hematopoietic cell types, including cells of the same type. 2B4/CD48 signaling cooperates with other receptor systems to either promote or inhibit NK and CD8+ T cell activation. The inhibitory activities are distinct from those of MHC I restricted inhibitory NK cell receptors. Ligation of 2B4 with antibodies or CD48 constructs can either directly trigger inhibitory signaling or disrupt an inhibitory interaction, leading to cellular activation. The inhibitory effect is associated with the long form of 2B4, while the activation is associated with the short form. 2B4 can also induce signaling through CD48.

别名: Natural killer cell receptor 2B4; NK cell activation-inducing ligand; NAIL; NKR2B4; h2B4; SLAM family member 4; SLAMF4; CD244; 2B4

Accession: Q9BZW8-2

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs04642   Recombinant Human Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His)   10ug   756.00   立即咨询
  abs04642   Recombinant Human Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His)   50ug   2100.00   立即咨询
  abs04642   Recombinant Human Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His)   500ug   9408.00   立即咨询
  abs04642   Recombinant Human Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His)   1mg   12800.00   立即咨询

产品更多信息请进入爱必信网站咨询

相关产品

同类推荐 更多
Recombinant Human Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His), 人蛋白Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His)由爱必信(上海)生物科技有限公司为您提供,货号abs04642,规格:10ug,CAS号:,如您想了解更多关于Recombinant Human Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His), 人蛋白Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His)价格、Recombinant Human Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His), 人蛋白Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His)结构式、批发、用途等信息,欢迎咨询。除供应Recombinant Human Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His), 人蛋白Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His)外,还可为您提供其他等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,爱必信客户服务电话,售前、售后均可联系。
Business information
工商信息 信息已认证
contact us
联系方式

详细地址

上海市浦东新区新浩路58号18号楼
当前位置: 爱必信 试剂 Recombinant Human Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His), 人蛋白Natural Killer Cell Receptor 2B4/SLAMF4/CD244 (C-6His)

关注

拨打电话

留言咨询