Recombinant Human Methionine Aminopeptidase 2/METAP2 (N-6His), 人蛋白Methionine Aminopeptidase 2/METAP2 (N-6His)|10ug|abs04649-爱必信(上海)生物科技有限公司

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产品描述：

产品名称：Recombinant Human Methionine Aminopeptidase 2/METAP2 (N-6His)

背景说明: Human Methionine Aminopeptidase 2 (METAP2, MAP2) is a member of the M24 family of metalloproteases. METAPs catalyze the removal of the initiator methionine residue from nascent peptides and are essential for cell growth. MAP2 binds 2 cobalt or manganese ions and contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. It is found in all organisms and is especially important because of its critical role in tissue repair and protein degradation. METAP2 plays an important role in the development of different types of cancer and has been a novel target for developing anti-cancer drugs. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amno-terminal methionine residue from nascent protein. MAP2 protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. It also plays a critical role in the regulation of protein synthesis.

描述: Recombinant Human Methionine Aminopeptidase 2 is produced by our Baculovirus expression system and the target gene encoding Ala2-Tyr478 is expressed with a 6His tag at the N-terminus.

氨基酸序列: HHHHHHAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPICDLYP NGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKYVMSWIKPG MTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTTVLQYDDICKIDFGTH ISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEIDGKTY QVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMK NFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDI KGSYTAQFEHTILLRPTCKEVVSRGDDY

别名: Methionine aminopeptidase 2; MAP 2; MetAP 2; p67; p67eIF2; Peptidase M; METAP2; MAP2

Accession: P50579

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Escherichia coli.

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Supplied as a 0.2 μm filtered solution of 20mM Tris, 500mM NaCl, 10% glycerol, pH8.0.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04649	Recombinant Human Methionine Aminopeptidase 2/METAP2 (N-6His)	10ug	882.00	立即咨询
abs04649	Recombinant Human Methionine Aminopeptidase 2/METAP2 (N-6His)	50ug	2646.00	立即咨询
abs04649	Recombinant Human Methionine Aminopeptidase 2/METAP2 (N-6His)	500ug	12936.00	立即咨询
abs04649	Recombinant Human Methionine Aminopeptidase 2/METAP2 (N-6His)	1mg	17600.00	立即咨询

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Recombinant Human Methionine Aminopeptidase 2/METAP2 (N-6His), 人蛋白Methionine Aminopeptidase 2/METAP2 (N-6His)由爱必信(上海)生物科技有限公司为您提供，货号abs04649，规格：10ug，CAS号：，如您想了解更多关于Recombinant Human Methionine Aminopeptidase 2/METAP2 (N-6His), 人蛋白Methionine Aminopeptidase 2/METAP2 (N-6His)价格、Recombinant Human Methionine Aminopeptidase 2/METAP2 (N-6His), 人蛋白Methionine Aminopeptidase 2/METAP2 (N-6His)结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Human Methionine Aminopeptidase 2/METAP2 (N-6His), 人蛋白Methionine Aminopeptidase 2/METAP2 (N-6His)外，还可为您提供其他等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，爱必信客户服务电话，售前、售后均可联系。

供货周期：	一周
品牌：	爱必信
规格：	10ug
货号：	abs04649
CAS号：