Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His), 小鼠蛋白Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His)|10ug|abs04661-爱必信(上海)生物科技有限公司

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产品描述：

产品名称：Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His)

背景说明: Osteoprotegerin (OPG, Tnfrsf11b) is a secreted protein that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts and endothelial cells. Regulation of its expression by estrogen, parathyroid hormone and cytokines is complex and changes with age. OPG acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. TRAIL decreases the release of OPG from cells that express it, while OPG inhibits TRAIL-induced apoptosis. Expression of RANK L on the cell surface, and thus its ability to stimulate osteoclastogenesis, is regulated by OPG by intracellular and extracellular mechanisms. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. It may also play a role in preventing arterial calcification.

描述:

Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 11B is produced by our Mammalian expression system and the target gene encoding Glu22-Leu401 is expressed with a 10His tag at the C-terminus.

氨基酸序列: ETLPPKYLHYDPETGHQLLCDKCAPGTYLKQHCTVRRKTLCVPCPDHSYTDSWHTSDECVYCSPV CKELQSVKQECNRTHNRVCECEEGRYLEIEFCLKHRSCPPGSGVVQAGTPERNTVCKKCPDGFFS GETSSKAPCIKHTNCSTFGLLLIQKGNATHDNVCSGNREATQKCGIDVTLCEEAFFRFAVPTKII PNWLSVLVDSLPGTKVNAESVERIKRRHSSQEQTFQLLKLWKHQNRDQEMVKKIIQDIDLCESSV QRHLGHSNLTTEQLLALMESLPGKKISPEEIERTRKTCKSSEQLLKLLSLWRIKNGDQDTLKGLM YALKHLKTSHFPKTVTHSLRKTMRFLHSFTMYRLYQKLFLEMIGNQVQSVKISCLGGGGSHHHHH HHHHH

别名: Tumor necrosis factor receptor superfamily member 11B; Osteoclastogenesis inhibitory factor; Osteoprotegerin; Tnfrsf11b; Ocif; Opg

Accession: O08712

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

储存/保存方法: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04661	Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His)	10ug	756.00	立即咨询
abs04661	Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His)	50ug	2100.00	立即咨询
abs04661	Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His)	500ug	9408.00	立即咨询
abs04661	Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His)	1mg	12800.00	立即咨询

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Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His), 小鼠蛋白Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His)由爱必信(上海)生物科技有限公司为您提供，货号abs04661，规格：10ug，CAS号：，如您想了解更多关于Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His), 小鼠蛋白Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His)价格、Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His), 小鼠蛋白Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His)结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Mouse Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His), 小鼠蛋白Tumor Necrosis Factor Receptor Superfamily Member 11B/Osteoprotegerin/TNFRSF11B (C-10His)外，还可为您提供其他等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，爱必信客户服务电话，售前、售后均可联系。

供货周期：	一周
品牌：	爱必信
规格：	10ug
货号：	abs04661
CAS号：