Recombinant Mouse CD40 ligand/CD40LG (N-6His), 小鼠蛋白CD40 ligand/CD40LG (N-6His)|10ug|abs04673-爱必信(上海)生物科技有限公司

Recombinant Mouse CD40 ligand/CD40LG (N-6His), 小鼠蛋白CD40 ligand/CD40LG (N-6His)

参考价：¥756

供货周期：

一周

品牌：

爱必信

规格：

10ug

货号：

abs04673

CAS号：

产品详情

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产品描述：

产品名称：Recombinant Mouse CD40 ligand/CD40LG (N-6His)

背景说明: CD40 Ligand, also known as TNFSF5, CD154, is a type II transmembrane glycoprotein member of the TNF superfamily. Mature mouse CD40 Ligand consists of a 22 amino acid (aa) cytoplasmic domain, a transmembrane segment, and a 214 aa extracellular region. CD40 Ligand is expressed as a homotrimer on platelets and activated T cells and B cells. It is up-regulated following stimulation of basophils, eosinophils, fibroblasts, mast cells, monocytes, natural killer cells, vascular endothelial cells, and smooth muscle cells. CD40 Ligand binds and activates CD40, which is expressed on the surface of B cells, dendritic cells,macrophages, monocytes, platelets, endothelial cells, and epithelial cells. Monomeric, dimeric, and trimeric forms of soluble CD40 Ligand bind to oligomeric CD40 on cell membranes. CD40 ligation by CD40 Ligand promotes B cell activation and T cell-dependent humoral responses. CD40 Ligand dysregulation on T cells and antigen presenting cells contributes to the immune deficiency associated with HIV infection and AIDS. It is also implicated in the pathology of multiple cardiovascular diseases including atherosclerosis, atherothrombosis, and restenosis.

描述: Recombinant Mouse CD40 ligand is produced by our Mammalian expression system and the target gene encoding Met112-Leu260 is expressed with a 6His tag at the N-terminus.

氨基酸序列: GSGSHHHHHHIEGRGGGSGGGSGGGSMQRGDEDPQIAAHVVSEANSNAASVLQWAKKGYYTMKSN LVMLENGKQLTVKREGLYYVYTQVTFCSNREPSSQRPFIVGLWLKPSSGSERILLKAANTHSSSQ LCEQQSVHLGGVFELQAGASVFVNVTEASQVIHRVGFSSFGLLKL

别名: CD40 Ligand; CD40LG;HIGM1; T-B cell-activating molecule; T-BAM; TNFSF5; tumor necrosis factor (ligand) superfamily member 5; Tumor necrosis factor ligand superfamily member 5

Accession: P27548

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs04673	Recombinant Mouse CD40 ligand/CD40LG (N-6His)	10ug	756.00	立即咨询
abs04673	Recombinant Mouse CD40 ligand/CD40LG (N-6His)	50ug	2100.00	立即咨询
abs04673	Recombinant Mouse CD40 ligand/CD40LG (N-6His)	500ug	9408.00	立即咨询
abs04673	Recombinant Mouse CD40 ligand/CD40LG (N-6His)	1mg	12800.00	立即咨询

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