Chelidonic acid|100mg|abs814785-爱必信(上海)生物科技有限公司

Chelidonic acid

参考价：¥630

供货周期：

一周

品牌：

爱必信

规格：

100mg

货号：

abs814785

CAS号：

99-32-1

产品详情

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产品描述：

产品名称：Chelidonic acid

描述:

Chelidonic acid is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid also shows anti-inflammatory activity. Chelidonic acid has potential to inhibit IL-6 production by blocking NF-κB and caspase-1. Chelidonic acid is a glutamate decarboxylase inhibitor, with a Ki of 1.2 μM.

别名: 白屈菜酸；Jerva acid；Jervaic acid； γ-Pyrone-2；6-dicarboxylic acid

CAS号: 99-32-1

靶点: NF-κB,Caspase-1,Glutamate decarboxylase

In vitro(体外研究): Chelidonic acid dose-dependently decreases IL-6 production at 0.1-10 μM, inhibits expression of IL-6 mRNA at 1-10 μM. Chelidonic acid (0.1-10 μM) decreases caspase-1 activation, nuclear NF-κB activation, and increases cytosol NF-κB activation. Chelidonic acid is a glutamate decarboxylase inhibitor, with a Ki of 1.2 μM. Chelidonic acid does not promote formation of apoenzyme or react with free pyridoxal-P.

分子式: C₇H₄O₆

外观: Beige to brown powder

In vivo(体内研究): Chelidonic acid (0.2, 2 mg/kg p.o.) attenuates allergic reaction induced by ovalbumin in mice.

分子量: 184.10

纯度: >98%

储存/保存方法: Store at -20°C

产品用途: 科研试剂，用于有机合成。

可溶性/溶解性: DMSO ：4 mg/mL (21.72 mM)

产品信息订购：

产品货号	产品名称	规格	价格	大包装及货期
abs814785	Chelidonic acid	100mg	630.00	立即咨询

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