供货周期: | 现货 |
品牌: | 爱必信 |
规格: | |
货号: | abs131123 |
CAS号: |
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抗体描述: 产品名称:Rabbit anti-SNAI2 Polyclonal Antibody 产品别名:dJ710H13.1; MGC10182; Neural crest transcription factor Slug; Protein sna; Protein snail homolog 1; Protein snail homolog 2; Protein snail homolog; Slug homolog zinc finger protein; Slug zinc finger protein; SLUGH; SLUGH 1; SLUGH1; SLUGH2; SNA; Sna protein; SNAH; SNAI 2; snai1; SNAI1_HUMAN; Snai2; SNAI2_HUMAN; Snail 2; Snail homolog 1 (Drosophila); Snail homolog 2; Snail2; WS 2D; WS2D; Zinc finger protein SLUG; Zinc finger protein SNAI1; Zinc finger protein SNAI2; 宿主:Rabbit 反应种属:Human;Mouse;Rat 克隆性:Polyclonal 保存方法:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles 产品描述:This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity.The tumor suppressor protein p53 induces Slug expression in gamma-irradiated cells; Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein Puma. Mutations in this gene may be associated with sporatic cases of neural tube defects. 用途范围: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
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