供货周期: | 现货 |
品牌: | 美国Neweast Biosciences |
规格: | 100 微升 |
货号: | 26163 |
CAS号: |
Anti-IDH2(R172K) Mouse Monoclonal Antibody/现货抗体2023更新文献 货号: 26163 |
基因符号: IDH2; D2HGA2; ICD-M; IDH; IDHM; IDP; IDPM; mNADP-IDH |
描述: Anti-IDH2(R172K) Mouse Monoclonal Antibody |
背景介绍: Isocitrate dehydrogenase (IDH) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. The isocitrate and isopropylmalate dehydrogenases family has three members, IDH1, IDH2 and IDH3. IDH2 plays a role in intermediary metabolism and energy production. Defects in IDH2 are the cause of D-2-hydroxyglutaric aciduria type 2 (D2HGA2). Somatic mosaic mutations of this protein have also been found associated to Ollier disease and Maffucci syndrome, and R172K IDH2 mutations do exist in diffusely infiltrative gliomas. |
免疫原: A synthetic peptide from the internal region of IDH2 which includes the mutation of R172K, human origin |
经过测试的应用: ELISA, WB, IHC |
推荐稀释比: ELISA: 1: 1000-1: 5000 WB: 1: 100-1: 1000 IHC: 1: 50-1: 100 IHC: 1: 10-1: 100 |
浓度: 1 mg/ml |
宿主: Mouse |
形式: Liquid |
克隆性: Monoclonal |
亚型: IgG |
纯度: Purified from ascites |
防腐剂: No |
成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
种属反应性: recognizes R172K mutant, but not wild-type IDH2 of vertebrates |
储存条件: Store at -20°C. Avoid repeated freezing and thawing Anti-IDH2(R172K) Mouse Monoclonal Antibody/现货抗体2023更新文献 |
蛋白质印迹: Anti-IDH2(R172K) Mouse Monoclonal Antibody/现货抗体2023更新文献 |
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Anti-IDH2(R172K) Mouse Monoclonal Antibody/现货抗体2023更新文献
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