阿齐沙坦

Product Name: Azilsartan

Cas号: 147403-03-0

分子式: C25H20N4O5

分子量: 456.45

MDL号: MFCD00916395

 A122333-10mg ≥98% (HPLC)

 A122333-250mg ≥98% (HPLC)

 A122333-50mg ≥98% (HPLC)

 A122333-10mg ≥98% (HPLC)

 A122333-250mg ≥98% (HPLC)

 A122333-50mg ≥98% (HPLC)

阿齐沙坦用途: 阿齐沙坦（又称阿齐沙坦酯，英语：Azilsartan）（INN） 是一款正处于研发中的治疗高血压症的血管紧张素II受体拮抗剂药物，多用于治疗高血压症，也是目前唯一处于末期临床的血管紧张素II受体拮抗剂（沙坦类）药物。

包装: A122333-50mgglass btl

A122333-250mgglass btl

A122333-10mgglass btl

贮存: 储存温度2-8°C

阿齐沙坦生化和生理学机理: Azilsartan is a highly potent and slowly dissociating Angiotensin II type 1 (AT1) receptor blocker (ARB) with an IC50 of 2.6 nM. It is the active form of Azilsartan medoxomil, used for treatment of hypertension. Azilsartan may also have potentially beneficial effects on metabolic syndrome including insulin sensitizing activity that may involve more than just blockade of AT(1) receptors.