产品详情
Product Name: Ivermectine
别名: | 伊维茵素 ;伊维菌素 |
CAS号: | 70288-86-7 |
分子式: | C48H74O14 |
分子量: | 875.09 |
MDL号: | MFCD00869511 |
介绍: | 稳定,在水中溶解度极低。 |
用途: | Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor; also modulates glutamate-GABA-activated chloride channels. |
贮存: | 储存温度 2-8°C |
生化和生理学机理: | Ivermectin (22,23-dihydroavermectin B1a + 22,23-dihydroavermectin B1b) is a broad-spectrum antiparasitic avermectin medicine. Ivermectin is positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor and the purinergic P2X4 receptor. Antihelmintic. Ivermectin also modulates glutamate- and GABA-activated chloride channels. Ivermectin potentiates glycine-gated currents at low concentrations (30 nM). |