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盐酸土霉素

95%

Product Name: Oxytetracycline hydrochloride

别名:盐酸土霉素 ;盐酸氧四环素,(4S,4aR,5S,5aR,6S,12aS)-4-二甲氨基-1,4,4a,5,5a,6,11,12a-八氢-3,5,6,10,12,12a-六羟基-6-甲基-1,11-二氧代-2-并四苯甲酰胺盐酸盐
CAS号:2058-46-0
分子式:C22H24N2O9·HCl
分子量:496.89
EINECS编号:218-161-2
MDL号:MFCD00135815

盐酸土霉素


介绍:溶解度:>100 g/L水,20 g/L 甲醇。
用途:靠阻止氨基酰-tRNA结合到30S亚单位上抑制蛋白合成。 抗菌谱: 革兰氏阴性和阳性细菌。 耐药性模式: 活性丧失, 核糖体保护, 四环素失活。
熔点:180℃
特定比重:1.71
贮存:密封2-8°C保存。
生化和生理学机理:Oxytetracycline inhibits translation which results in cell death. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic so it can easily pass through a cell membrane and passively diffuses through channels in the bacterial membrane.

盐酸土霉素