产品详情
Product Name: Oxytetracycline hydrochloride
别名: | 盐酸土霉素 ;盐酸氧四环素,(4S,4aR,5S,5aR,6S,12aS)-4-二甲氨基-1,4,4a,5,5a,6,11,12a-八氢-3,5,6,10,12,12a-六羟基-6-甲基-1,11-二氧代-2-并四苯甲酰胺盐酸盐 |
CAS号: | 2058-46-0 |
分子式: | C22H24N2O9·HCl |
分子量: | 496.89 |
EINECS编号: | 218-161-2 |
MDL号: | MFCD00135815 |
介绍: | 溶解度:>100 g/L水,20 g/L 甲醇。 |
用途: | 靠阻止氨基酰-tRNA结合到30S亚单位上抑制蛋白合成。 抗菌谱: 革兰氏阴性和阳性细菌。 耐药性模式: 活性丧失, 核糖体保护, 四环素失活。 |
熔点: | 180℃ |
特定比重: | 1.71 |
贮存: | 密封2-8°C保存。 |
生化和生理学机理: | Oxytetracycline inhibits translation which results in cell death. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic so it can easily pass through a cell membrane and passively diffuses through channels in the bacterial membrane. |
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