盐酸小檗碱水合物
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Product Name: Berberine Chloride Hydrate
| 别名: | 氯化黄连素水合物，小檗碱盐酸盐;C.I. 75160;盐酸黄连素;自然黄18;633-65-8;相关CAS号:2086-83-1 |
| CAS号: | 141433-60-5 |
| 分子式: | C20H18ClNO4·xH2O |
| 分子量: | 371.82(as Anhydrous) |
| EINECS编号: | 211-195-9 |
| MDL号: | MFCD00011939 |
盐酸小檗碱水合物
| 介绍: | 一种生物碱，CAS号为633-65-8的为无水物 |
| 用途: | 1、用于在肥大细胞中肝素钠的荧光染色。 2、一种生物碱，带有弱的抗生素特性，细菌多重耐药外排泵（MDR efflux pumps）的底物。 berberine的抗微生物活性可被MDR抑制剂5′-methoxyhydnocarpin (5′-MHC)强化。Berberine调控肝癌细胞Pgp基因的表达。 |
| 熔点: | 200℃ |
| 生化和生理学机理: | An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5′-methoxyhydnocarpin (5′-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs. |
盐酸小檗碱水合物
