产品详情
5-(4-苯氧基丁氧基)补骨脂素（PAP-1）
98%
Product Name: 5-(4-Phenoxybutoxy)psoralen
| 别名: | 4-(4-苯氧基丁氧基)-7H-呋喃并(3,2-g)(1)苯并吡喃-7-酮;PAP-1；Kv1.3抑制剂 |
| CAS号: | 870653-45-5 |
| 分子式: | C21H18O5 |
| 分子量: | 350.36 |
| MDL号: | MFCD11114059 |
5-(4-苯氧基丁氧基)补骨脂素（PAP-1）
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| 用途: | Kv1.3钾离子通道的选择性抑制剂。 |
| 贮存: | 储存温度 2-8°C，避光保存 |
| 敏感性: | 对光敏感 |
| 生化和生理学机理: | PAP-1 is selective inhibitor of Kv1.3, voltage-gated K+ channel. PAP-1 (EC50=2 nM) potently inhibits human T effector memory cell proliferation and delayed hypersensitivity. Effective orally or intraperitoneally. 5-(4-Phenoxybutoxy)psoralen has 23-fold selectivity for Kv1.3 over Kv1.5, and 33-125-fold selectivity over other Kv1 family channels. In treatment of multiple sclerosis |