英文名称    BEGAIN    

中文名称    大脑富含鸟苷酸激酶相关蛋白抗体    

别    名    BEGAIN; BEGIN; Brain enriched guanylate kinase associated protein; Brain-enriched guanylate kinase-associated homolog (rat); KIAA1446; SAP90/PSD95 Associated Proteins; SAPAP; BEGIN_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  神经生物学  细胞类型标志物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 大脑富含鸟苷酸激酶相关蛋白抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    65kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human BEGAIN    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

大脑富含鸟苷酸激酶相关蛋白抗体产品介绍    background:

BEGAIN is a 593 amino acid protein that localizes to cytoplasm and membrane. BEGAIN interacts with PSD-95 and SAPAP1 and forms a ternary complex and may sustain the structure of the postsynaptic density (PSD). BEGAIN is a novel PSD component associated with the core complex of PSD-95 and SAPAP. Because BEGAIN and SAPAP interact with the same region of PSD-95, BEGAIN and SAPAP may compete for the binding to PSD-95 and cannot interact with PSD-95 simultaneously. The C-terminal region of BEGAIN is involved in the interaction with PSD-95 whereas the N-terminal region has a coiled-coil structure that may interact with other molecules. BEGAIN is specifically expressed in brain and enriched in the PSD fraction. BEGAIN is also expressed in neurons and enriched at synaptic junctions, and is likely involved in the organization of synaptic junction components.

Function:
Brain-enriched guanylate kinase-associated protein (BEGAIN) interacts with postsynaptic density (PSD)-95/synapse-associated protein (SAP) 90. BEGAIN has been detected in nuclei and at synapses in neurons.    

大脑富含鸟苷酸激酶相关蛋白抗体

hz-1287 AQP-3(Mouse Aquaporin 3) ELISA Kit  小鼠水通道蛋白3

hz-1288 AQP-1(Mouse Aquaporin 1) ELISA Kit  小鼠水通道蛋白1

hz-1288 GP-MM ELISA Kit  大鼠糖原磷酸化酶同工酶MM

hz-1288 Human Oncogene Protein p190/bcr-abl ELISA Kit  人癌基因蛋白质p190/bcr-abl

hz-1289 GP-BB ELISA Kit  大鼠糖原磷酸化酶同工酶BB

hz-1289 BTA(Human Bladder tumor antigen) ELISA Kit  人膀胱肿瘤抗原

hz-1289 AQP-0(Mouse Aquaporin 0) ELISA Kit  小鼠水通道蛋白0

hz-1290 AQP-2(Mouse Aquaporin 2) ELISA Kit  小鼠水通道蛋白2

hz-1290 MK(Human Midkine) ELISA Kit  人中期因子

hz-1290 TAb ELISA Kit  大鼠甲状腺素抗体

hz-1291 Bid(Human BH3 interacting domain death agonist) ELISA Kit  人BH3结构域凋亡诱导蛋白

hz-1291 TRAb ELISA Kit  大鼠抗促甲状腺素受体抗体

hz-1291 TG(Mouse Thyroglobulin) ELISA Kit  小鼠甲状腺球蛋白

hz-1292 INH-A(Mouse Inhibin) ELISA Kit  小鼠抑制素A

hz-1292 CA ELISA Kit  大鼠儿茶酚胺

hz-1292 Bcl-2(Human B-cell leukhzia/lymphoma 2) ELISA Kit  人B细胞淋巴瘤因子2

hz-1293 Beta-CG(Mouse Chorionic Gonadotrophin Beta) ELISA Kit  小鼠绒毛膜促性腺激素β

hz-1293 TSGF(Human Tumor Specific Growth Facter/tumor supplied group of factor) ELISA Kit  人肿瘤特异生长因子/肿瘤相关因子

hz-1293 IL-27 ELISA Kit  大鼠白介素27

hz-1294 IL-33 ELISA Kit (human)  人白介素23

hz-1294 SHBG(Mouse sex hormone-binding globulin) ELISA Kit  小鼠性激素结合球蛋白

hz-1294 PEDF(Human pigment epithelium-derived factor) ELISA Kit  人色素上皮衍生因子

hz-1295 CC16(Human Clara cell protein) ELISA Kit  人克拉拉细胞蛋白

hz-1295 DHEA-S7(Mouse Dhzydroepiandrosterone S7) ELISA Kit  小鼠脱氢表雄酮S7

hz-1295 CT-1 ELISA Kit  大鼠心肌营养素1

hz-1296 Alpha-Fodrin IgG/IgA ELISA Kit  大鼠抗α-胞衬蛋白抗体IgG/IgA

hz-1296 DHEA(Mouse Dhzydroepiandrosterone) ELISA Kit  小鼠脱氢表雄酮

hz-1296 HIF-1 Alpha (Human hypoxia-inducible factor 1 Alpha) ELISA Kit  人低氧诱导因子1α

hz-1297 MC Ab(Human melanocyte antibody) ELISA Kit  人黑色素细胞抗体

hz-1297 Lp- Alpha ELISA Kit  大鼠脂蛋白α

hz-1297 HMGB-1(Mouse High mobility group protein B1) ELISA Kit  小鼠高迁移率族蛋白B1