产品详情
英文名称 CRIM1
中文名称 富含半胱氨酸运动神经元蛋白1抗体
别 名 Cysteine-rich motor neuron 1 protein; CRIM-1; Cysteine-rich repeat-containing protein S52; Processed cysteine-rich motor neuron 1protein; CRIM 1; CRIM1; Cysteine rich motor neuron 1 protein; Cysteine rich repeat containing protein S52; Cysteine rich transmembrane BMP regulator 1 (chordin like); Cysteine rich transmembrane BMP regulator 1; MGC138194; Processed cysteine rich motor neuron 1 protein; S52; CRIM1_HUMAN.
说 明 书 0.1ml 0.2ml
研究领域 心血管 细胞生物 染色质和核信号 神经生物学 信号转导 血管内皮细胞 细胞骨架 细胞外基质
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 富含半胱氨酸运动神经元蛋白1抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 110kDa
细胞定位 细胞膜 分泌型蛋白
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse CRIM1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
富含半胱氨酸运动神经元蛋白1抗体产品介绍 background:
CRIM1 interacts with BMP4 (bone morphogenic protein 4) and BMP7 and modulates BMP activity by affecting their processing and delivery to the cell surface. By interacting with growth factors implicated in motor neuron differentiation and survival, it may play a role in CNS development. It may also play a role in capillary formation and maintenance during angiogenesis.
Function:
May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival.
May play a role in capillary formation and maintenance during angiogenesis.
Modulates BMP activity by affecting its processing and delivery to the cell surface.
富含半胱氨酸运动神经元蛋白1抗体
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