产品详情
英文名称 CCR6
中文名称 细胞表面趋化因子受体6抗体
别 名 CKR6; C-C chemokine receptor type 6; BN 1; BN1; C C chemokine receptor type 6; C C CKR 6; CC chemokine receptor type 6; CC CKR 6; CC R6; CCCKR6; CCR 6; CD 196; CD196; CD196 antigen; Chemokine (C C motif) receptor 6; Chemokine (C C) receptor 6; Chemokine (CC motif) receptor 6; Chemokine (CC) receptor 6; Chemokine receptor 6; Chemokine receptor like 3; CKR 6; CKR L3; CKRL3; CMKBR 6; CMKBR6; DCR 2; DCR2; DRY 6; DRY6; G protein coupled receptor 29; GPR 29; GPR CY4; GPR29; GPRCY 4; GPRCY4; LARC receptor; Seven transmembrane receptor lymphocyte 22; STRL 22; STRL22; CCR6_HUMAN.
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 信号转导 转录调节因子 细胞表面分子
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 细胞表面趋化因子受体6抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CCR6 (151-241aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
细胞表面趋化因子受体6抗体产品介绍 background:
CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. It is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP 3 alpha). This receptor has been shown to be important for B lineage maturation and antigen driven B cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. CCR6 has been reported to be expressed in intestine, colon, liver, lymph node, spleen, lung, blood, umbilical cord, placenta, skin, and pancreas. It has also been reported to be expressed in lymphocytes, T cells, and B cells.
Function:
Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.
细胞表面趋化因子受体6抗体
hz-0248P BDNF (Brain-derived Neurotrophin factor) 脑源神经营养因子(脑衍化神经营养因子)(多肽片断抗原)
hz-2249P ACA11 peptide 拟南芥ACA11蛋白多肽抗原
hz-2247P AHA3 peptide 植物蛋白AHA3抗原(拟南芥)
hz-0217P bFGF 碱性成纤维细胞生长因子(多肽抗原)
hz-1004P ACE2(Angiotensin converting enzyme 2) 血管紧张素转换酶2抗原
hz-0044P BNP 脑钠素(多肽抗原)
hzb-0044P BNP/Biotin 生物素化脑钠素多肽
hz-0489P BrdU (Bromodeoxyuridine) 溴脱氧尿苷
hz-0324P C5 过敏毒素C5(补体C5)抗原
hz-0091P CA125 卵巢癌抗原
hz-2190P CK19 细胞角蛋白19抗原
hz-0043P CAD(Caspase-Activated Deoxyribonuclease) Caspase 激活的脱氧核糖核酸酶(抗原)
hz-3550P MYOG 肌红蛋白抗原
hz-0095P Calponin 1 钙调节蛋白-1(抗原)
hz-3679P COMP 软骨寡聚基质蛋白抗原
hz-0169P Caspase-1 (ICE; CASP-1;P45) 天冬氨酸-胱氨酸特异性蛋白酶家族(抗原)
hz-0081P Caspase-3 (CPP32) 半胱胺酸蛋白酶蛋白-3(抗原)
hz-0084P Caspase-6 (NT) 半胱胺酸蛋白酶蛋白-6(抗原)
hz-0151P Caspase-6 (CT) 半胱胺酸蛋白酶蛋白-6(抗原)
hz-4002P phospho-AMPK alpha 1(Thr172) peptaide 磷酸化腺苷单磷酸活化蛋白激酶α1抗原
hz-0049P Caspase-9 白介素1-β转化酶样凋亡蛋白酶6(抗原)
hz-0050P Caspase-9 白介素1-β转化酶样凋亡蛋白酶6(抗原)
hz-2105P AD7C-NTP/NTP/AF peptide 神经丝蛋白蛋白多肽抗原(人)
hz-0092P Caspase-10 半胱胺酸蛋白酶-10(抗原)
hz-0053P Caspase-13 半胱胺酸蛋白酶蛋白-13(抗原)
hz-0079P CD19(B-lymphocyte antigen CD19) CD19
hz-4532PB Clenbuterol Hydrochloride/BSA 盐酸克仑特罗偶联牛血清白蛋白BSA
hz-4532PK Clenbuterol Hydrochloride/KLH 盐酸克仑特罗偶联血蓝蛋白KLH
hz-4533PB Estradiol/BSA 雌二醇偶联牛血清白蛋白
hz-2167P DRADA/ADAR1(Double-stranded RNA-specific adenosine deaminase)N terminal 双链RNA腺苷酸脱氨基酶抗原(N端)
hz-2168P DRADA/ADAR1(Double-stranded RNA-specific adenosine deaminase) 双链RNA腺苷酸脱氨基酶抗原
hz-4545PB Ractopamine/BSA 莱克多巴胺与牛血清白蛋白偶联物