产品详情
英文名称 CD108
中文名称 轴突生长因子CD108抗体
别 名 semaphorin 7A; CD 108; CD108; CD108 antigen; CDw108; H Sema K1; H Sema L; JMH; JMH blood group antigen; John Milton Hagen blood group H Sema K1; John Milton Hargen human blood group Ag; MGC126692; MGC126696; Sema domain immunoglobulin domain (Ig) and GPI membrane anchor 7A; Sema L; Sema7a; SEMAK1; SEMAL; Semaphorin 7A GPI membrane anchor; Semaphorin K1; Semaphorin L; Semaphorin7a; SEM7A_HUMAN.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 免疫学 生长因子和激素 转录调节因子
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 轴突生长因子CD108抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 66kDa
细胞定位 细胞膜 细胞外基质
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Sema7A
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
轴突生长因子CD108抗体产品介绍 background:
Semaphorin 7a is required for central and peripheral axon growth and is required for proper axon tract formation during embryonic development. Semaphorin 7a is also involved in modulating immune function. Semaphorin 7a expression is highest in the brain and increases in late embryonic and postnatal stages. The Semaphorins constitute a large family of secreted and membrane-tethered cell signaling molecules. They have functions in neural development, immunology, cardiac growth, vascular development, lung morphogenesis and axial bone patterning. Semaphorins are defined by the presence of a conserved Sema domain at the N-terminus. These proteins can be classified into eight classes depending on their structure and species origin. Classes 3 through 7 are found in vertebrates; class 3 are secreted, class 7 are GPI-anchored, and class 4 through 6 are transmembrane proteins.
Function:
Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
轴突生长因子CD108抗体
hz-0369P-APhz Rabbit IgM/APC 荧光素APC标记兔IgM
hz-0346P-APhz Rat IgM/APC 荧光素APC标记大鼠IgM
hz-0789P-APhz Insulin Protein /APC 荧光素APC标记猪胰岛素蛋白
hz-P0002-APhz KLH/APC 荧光素APC标记血蓝蛋白
hz-P0003-APhz OVA/APC 荧光素APC标记鸡卵白蛋白
hz-0945P-APhz HSA(Human sermu albumin)/APC 荧光素APC标记人血白蛋白
hz-2179P-APhz AACT/APC 荧光素APC标记胰糜蛋白酶
hz-0437P-hzy3 Streptavidin/Cy3 荧光素Cy3标记链霉亲和素
hz-0312P-hzy3 Avidin/Cy3 荧光素Cy3标记亲合素
hz-0362P-hzy3 Protein A/Cy3 Cy3标记蛋白A
hz-0295P-hzy3 Rabbit IgG/Cy3 荧光素Cy3标记兔IgG(细胞流式同型对照)
hz-0296P-hzy3 Mouse IgG/Cy3 荧光素Cy3标记小鼠IgG(细胞流式同型对照)
hz-0294P-hzy3 Goat IgG/Cy3 荧光素Cy3标记羊IgG(细胞流式同型对照)
hz-0293P-hzy3 Rat IgG/Cy3 荧光素Cy3标记大鼠IgG(细胞流式同型对照)
hz-0326P-hzy3 Bovine IgG/Cy3 荧光素Cy3标记牛IgG
hz-0327P-hzy3 Bovine IgM/Cy3 荧光素Cy3标记牛IgM
hz-0310P-hzy3 Chicken IgG/Cy3 荧光素Cy3标记鸡IgG
hz-0314P-hzy3 Chicken IgM/Cy3 荧光素Cy3标记鸡IgM
hz-0303P-hzy3 dog IgG/Cy3 荧光素Cy3标记狗IgG
hz-0373P-hzy3 dog IgM/Cy3 荧光素Cy3标记狗IgM
hz-0370P-hzy3 Goat IgM/Cy3 荧光素Cy3标记羊IgM
hz-0358P-hzy3 Guinea pig IgG/Cy3 荧光素Cy3标记豚鼠IgG
hz-0375P-hzy3 Guinea pig IgM/Cy3 荧光素Cy3标记豚鼠IgM
hz-0308P-hzy3 Horse IgG/Cy3 荧光素Cy3标记马IgG
hz-0374P-hzy3 Horse IgM/Cy3 荧光素Cy3标记马IgM
hz-0297P-hzy3 human IgG/Cy3 荧光素Cy3标记人IgG
hz-0345P-hzy3 human IgM/Cy3 荧光素Cy3标记人IgM
hz-0360P-hzy3 human IgA/Cy3 荧光素Cy3标记人IgA
hz-0335P-hzy3 Monkey IgG/Cy3 荧光素Cy3标记猴IgG
hz-0336P-hzy3 Monkey IgM/Cy3 荧光素Cy3标记猴IgM