产品详情
英文名称 CD44v10
中文名称 CD44V10抗体
别 名 LHR; BA-1; CD 44; CD44; CD44 antigen; CD44 molecule; CD44_HUMAN; CDw44; Cell surface glycoprotein CD44; chondroitin sulfate proteoglycan 8; ECMR-III; Epican; Extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; hematopoietic cell E- and L-selectin ligand; Heparan sulfate proteoglycan; Hermes antigen; homing function and Indian blood group system; HSA; HUTCH-I; HUTCH1; Hyaluronate receptor; MDU2; MDU3; MIC4; MUTCH1; PGP-1; PGP1; Phagocytic glycoprotein 1; Phagocytic glycoprotein I.
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 细胞生物 免疫学 细胞表面分子
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Rabbit,
产品应用 WB=1:100-500 ELISA=1:2000-5000 IHC-P=1:50-200 IHC-F=1:50-200 Flow-Cyt=1:50-200 IF=1:50-200 CD44V10抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 82kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD44v10
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CD44V10抗体产品介绍 background:
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008].
Function:
Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
CD44V10抗体
hz-0016P TY3H ( Tyrosine Hydroxylase ) 酪氨酸羟化酶(抗原)
hz-0159P Tubulin-Alpha 微管蛋白(抗原)
hz-1453P Cav-1/ETM1 peptide 细胞质膜微囊蛋白-1抗原
hz-1165P Beta-catenin/ Beta-cats β-连环蛋白抗原(β-β链接素)
hz-2063P p- Beta catenin(p-beta Catenin(phosphor-Y142)) 磷酸化β-连环蛋白抗原
hz-0210P Tubulin- Beta 微管蛋白(抗原)
hz-0452P NAIF1 protein( CB12-327) 核凋亡诱导因子蛋白1(多肽)
hz-1500P cath-B/CB(Cathepsin B) 组织蛋白酶B抗原
hz-1508P cath-L/CL peptide 组织蛋白酶L抗原
hz-1134P CBFA1/RUNX2 (Runt-related Transcription Factor 2) 成骨特异性转录因子(多肽)
hz-1397P CBP(CREB-binding protein) CREB结合蛋白抗原
hz-1421P CBX3/HP1 gamma 染色盒同源物3抗原
hz-0955P CBX5(Chromobox Homolog 5) CBX5(多肽)
hz-1487P CC16(Clara cell protein 16) peptide 克拉拉细胞蛋白(Clara细胞分泌蛋白)抗原
hz-0562P CCR-2/5(CC chhzokine receptor 2/5) CC趋化因子受体2/5抗原
hz-2450P CCL1/TCA3/I-309 嗜酸粒细胞趋化蛋白CCL1抗原
hz-1324P CCL5/RANTES(regulated on activation normal T cell expressed and secreted) 活化T细胞表达和分泌的调节因子抗原
hz-2475P CCL4/MIP-1 Beta(Macrophage Inflammatory Protein 1 beta) 巨噬细胞炎性蛋白1β抗原
hz-1268P MIP3 Alpha/CCL20(Macrophage inflammatory ptotein 3 alpha) 巨噬细胞炎性蛋白3α抗原
hz-2478P CCL12/MCP-5(C-C motif chhzokine 12) 单核细胞趋化蛋白5抗原
hz-2479P CCL14/HCC-1(C-C motif chhzokine 14) 嗜酸粒细胞趋化蛋白14抗原
hz-1761P ABCD-1/CCL22 嗜酸粒细胞趋化蛋白22抗原
hz-2454P MIP-3 beta/ELC/CCL19(Macrophage Inflammatory Protein 3 Beta) 巨噬细胞炎性蛋白19抗原
hz-1762P CCL26(Eotaxin 3) 嗜酸粒细胞趋化蛋白3抗原
hz-1169P CCR-1(CC chhzokine receptor 1) 细胞表面趋化因子受体1抗原
hz-1167P CCR-3(CC chhzokine receptor 3) CC趋化因子受体3抗原
hz-1671P CCR-2A(C-C Chhzokine receptor 2A) 细胞表面趋化因子受体2A抗原
hz-1168P CCR-4(C-C chhzokine receptor 4) 细胞表面趋化因子受体4抗原
hz-1542P CCR-6/CD196 peptide 细胞表面趋化因子受体6抗原
hz-1628P CXCR6(CXC-chhzokine receptor 6) peptide 细胞表面趋化因子受体6抗原
hz-1305P CCR-7(CC chhzokine receptor 7) CC趋化因子受体7(多肽)
hz-1502P CXCL10/IP-10 CXCL10趋化因子10/干扰素诱导蛋白10抗原
hz-0279P VEGF(Vascular endothelial growth factor) 血管内皮生长因子(多肽抗原)