英文名称    CACNA1A    

中文名称    电压依赖性钙通道Cav2.1抗体    

别    名    APCA; BI; Brain calcium channel 1; Brain calcium channel I; Cach4; Cacn3; Cacna1a; Cacnl1a4; Calcium channel alpha 1A subunit; Calcium channel L type alpha 1 polypeptide; Calcium channel L type alpha-1 polypeptide isoform 4; Calcium channel voltage dependent, P/Q type alpha 1A subunit; CAV2.1; EA2; FHM; HPCA; MHP; MHP1; RAT brain class A; RBA-I; SCA6; Voltage-dependent P/Q-type calcium channel alpha-1A subunit; Voltage-gated calcium channel alpha subunit Cav2.1; CAC1A_HUMAN.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  免疫学  通道蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Rabbit,     

产品应用    ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 电压依赖性钙通道Cav2.1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    282kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human CACNA1A    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

电压依赖性钙通道Cav2.1抗体产品介绍    background:

Cav2.1 is a voltage-sensitive calcium channels (VSCC) which belongs to the calcium channel alpha-1 subunit family. Cav2.1 mediates the entry of calcium ions into excitable cells and is also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Cav2.1 (isoform alpha-1A) gives rise to P and/or Q-type calcium currents. Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the pore-forming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.

Function:
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by the funnel toxin (Ftx) and by the omega-agatoxin-IVA (omega-Aga-IVA). They are however insensitive to dihydropyridines (DHP), and omega-conotoxin-GVIA (omega-CTx-GVIA).    

电压依赖性钙通道Cav2.1抗体

hz-7793R CLASP2  细胞连接相关蛋白2抗体

hz-7794R DIS3  有丝分裂控制蛋白dis3抗体

hz-7795R DPEP3  膜二肽酶3抗体

hz-7796R DSN1  着丝粒相关蛋白DSN1抗体

hz-7797R DUSP13  双特异性磷酸酶13抗体

hz-7798R Flotillin 1  脂阀结构蛋白1抗体

hz-7799R GAJ/MND1  减数分裂核分裂蛋白1抗体

hz-7800R GLP2R  胰高血糖素样肽2受体抗体

hz-1116R AMPK beta 1  腺苷单磷酸活化蛋白激酶β1抗体

hz-7801R GPIP137  糖磷脂酰肌醇锚定蛋白137抗体

hz-7802R GRASP65  高尔基体外周膜蛋白p65抗体

hz-3967R AMPK beta 2  腺苷单磷酸活化蛋白激酶β2抗体

hz-7803R HCF-1  宿主细胞因子1抗体

hz-7804R KIF15  驱动蛋白家族成员15抗体

hz-7805R KIFC1  驱动蛋白家族成员C1抗体

hz-3026R phospho-AMPK beta 1(Ser108)  磷酸化腺苷单磷酸活化蛋白激酶β1抗体

hz-3027R phospho-PRKAB1(Ser182)  磷酸化腺苷单磷酸活化蛋白激酶β1抗体

hz-3911R AMPK gamma 1  腺苷酸活化蛋白激酶γ1抗体

hz-7806R KLHDC5  kelch样蛋白5抗体

hz-4017R phospho-C-Myc(Thr358)  磷酸化致癌基因C-Myc抗体

hz-4018R phospho-C-Myc(Thr373)  磷酸化致癌基因C-Myc抗体

hz-7807R KLHL22  Kelch样蛋白22抗体

hz-7808R KNTC1/Kinetochore  着丝点关联蛋白1抗体

hz-3968R AMPK gamma 3/PRKAG3  腺苷酸活化蛋白激酶γ3抗体

hz-7809R LRRC62  富含亮氨酸重复蛋白62抗体

hz-7810R MFAP1  微原纤维胶原相关蛋白1抗体

hz-7811R MNS1  减数分裂特异核结构蛋白1抗体

hz-7812R MPP9/MPHOSPH9  有丝分裂细胞周期蛋白MPP9抗体

hz-7813R NEDD1  神经前体细胞表达蛋白1抗体

hz-7814R NEK1  丝氨酸/苏氨酸蛋白激酶NEK1抗体

hz-7815R NEK8  丝氨酸/苏氨酸蛋白激酶NEK8抗体

hz-7816R NSP5  核结构蛋白5抗体

hz-5980R n-Myc  致癌基因n-Myc抗体