产品详情
英文名称 phospho-CHEK1 (Ser280)
中文名称 磷酸化细胞周期检测点激酶1抗体
别 名 Chk1 (Phospho-Ser280); CHEK1 (phospho Ser280); CHEK1 (phospho Ser280); p-CHEK1 (Ser280); Cell cycle checkpoint kinase; Checkpoint, S. pombe, homolog of, 1; Checkpoint kinase 1; Checkpoint kinase 1 homolog (S. pombe); CHEK 1; CHEK-1; CHEK1; Chk 1; Chk1; CHK1 checkpoint homolog (S. pombe); EC 2.7.11.1; rad27; Serine/threonine protein kinase Chk1; Serine/threonine-protein kinase CHK1; STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae); C85740; CHK1_HUMAN.
说 明 书 0.1ml
产品类型 磷酸化抗体
研究领域 肿瘤 免疫学 染色质和核信号 信号转导 细胞周期蛋白 激酶和磷酸酶
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 磷酸化细胞周期检测点激酶1抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
细胞定位 细胞核 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from mouse CHEK1 around the phosphorylation site of Ser280
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
磷酸化细胞周期检测点激酶1抗体产品介绍 background:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011].
磷酸化细胞周期检测点激酶1抗体
hz-11223R ATRIP/TREX1 系统性红斑狼疮相关蛋白TREX1抗体
hz-11224R phospho-ATRIP (Ser68+Ser72) 系统性红斑狼疮先关蛋白TREX1抗体
hz-11225R Phospho-ATRIP (Ser224) 系统性红斑狼疮先关蛋白TREX1抗体
hz-11226R Phospho-CHEK1 (Ser296) 磷酸化细胞周期检测点激酶1抗体
hz-11227R Microcephalin 1/BRIT1 小脑症基因1/认知相关蛋白抗体
hz-11228R Phospho-JunB (Thr102/Thr104) 磷酸化活化蛋白激酶B抗体
hz-11229R OTUB1 泛素特异性蛋白酶OTB1抗体
hz-11230R RAD50 DNA修复蛋白Rad50抗体
hz-5374R phospho-GIT1(Tyr510) 磷酸化G蛋白偶联受体激酶相互作用蛋白1
hz-11231R RECQL5 RecQ解旋酶样蛋白5抗体
hz-11232R RECQL5 RecQ解旋酶样蛋白5抗体
hz-11233R RPA70 单链结合蛋白70抗体
hz-11234R Miz1/ZNF60 锌指蛋白60抗体
hz-11235R GRK6 G蛋白偶联受体激酶6抗体
hz-11236R Lefty/TGF beta 4 转化生长因子β4抗体TGF β4
hz-11237R TCF12/HEB 转录因子12抗体
hz-11238R SHANK2 富含脯氨酸突触相关蛋白SHANK2抗体
hz-11239R CREB-H/CREB3L3 环腺苷酸应答元件结合蛋白H抗体
hz-11240R phospho-Tau protein(Ser202) 磷酸化微管相关蛋白抗体
hz-11241R AP2M1/AP-2? 接头相关蛋白复合体AP-2μ链1抗体
hz-11242R Phospho-AP2M1 (Thr156) 磷酸化接头相关蛋白复合体AP-2μ链1抗体
hz-11243R Rab17 RAS癌基因相关蛋白RAB17抗体
hz-11244R RAB38 G蛋白结合蛋白RAB38抗体
hz-4221R TM7SF2/DHCR14A 脱氢胆固醇还原酶14抗体
hz-4113R HMG14/HMGN1 高迁移率核小体结合蛋白1
hz-4111R G3BP1 Ras GTP酶活化蛋白结合蛋白1抗体
hz-4248R ORP150 氧气调节蛋白150抗体
hz-0630R AT1R/AGTR1 血管紧张素Ⅱ-1型受体抗体
hz-2097R AT1R/AGTR1 血管紧张素Ⅱ-1型受体抗体
hz-5376R phospho-G3BP1(Ser232) 磷酸化Ras GTP酶活化蛋白结合蛋白1抗体
hz-5384R phospho-HMGN1(Ser20+Ser24) 磷酸化高迁移率核小体结合蛋白1
hz-0517R ATF1 活化转录因子1抗体
hz-4608R CUEDC2/CUE domain containing 2 CUE结构域蛋白2抗体
hz-4223R TRAP220/MED1 甲状腺受体相关蛋白220抗体
hz-5700R phospho-TRAP220/MED1(Thr1457) 磷酸化甲状腺受体相关蛋白220抗体