产品详情
英文名称 C19orf46
中文名称 19号染色体开放阅读框46抗体
别 名 Nesprin-4; Nesprin4; Nesprin 4; Chromosome 19 open reading frame 46; FLJ36445; Hypothetical protein LOC163183; SYNE4_HUMAN.
说 明 书 0.1ml 0.2ml
研究领域 心血管 细胞生物 免疫学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Horse, Rabbit,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 19号染色体开放阅读框46抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 44kDa
细胞定位 细胞核 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human C19orf46
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
19号染色体开放阅读框46抗体产品介绍 background:
C19orf46 is a 404 amino acid single-pass type IV membrane protein that belongs to the nesprin family. C19orf46 partcipates in the establishment of secretory epithelial morphology by inducing kinesin-dependent apical migration of the centrosome and Golgi apparatus as well as basal localization of the nucleus. C19orf46 interacts with UKHC and KCL1, and exists as two alternatively spliced isoforms. C19orf46 contains a KASH domain, which consists of a transmembrane motif, mediates nuclear enevelop targeting and binds to the SUN domain of SUN1 and SUN2. C19orf46 is encoded by a gene located on human chromosome 19, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA.
Function:
Contributes to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus (By similarity).
19号染色体开放阅读框46抗体
hz-9217R CST9/Cystatin 9 胱抑素9/半胱氨酸蛋白酶抑制剂9抗体
hz-9218R Cystatin S 胱抑素S/半胱氨酸蛋白酶抑制剂S抗体
hz-9219R C1orf149 1号染色体开放阅读框149抗体
hz-9220R C1orf187 1号染色体开放阅读框187抗体
hz-9221R C1orf177 1号染色体开放阅读框177抗体
hz-9222R C1orf183 1号染色体开放阅读框183抗体
hz-9223R RNF70 环指蛋白70抗体
hz-9224R RNF41 环指蛋白41抗体
hz-9225R RNF14 环指蛋白14抗体
hz-9226R RNF157 环指蛋白157抗体
hz-9227R RNF144 E3泛素蛋白连接酶144A抗体
hz-9228R RNF149 环指蛋白149抗体
hz-9229R RNF156 环指蛋白156抗体
hz-9230R RNF158 心脏蛋白磷酸酶1结合蛋白/环指蛋白158抗体
hz-9231R RNF166 环指蛋白166抗体
hz-9232R RNF167 环指蛋白167抗体
hz-9233R RNF180 环指蛋白180抗体
hz-9234R CREG1 E1A激活基因刺激蛋白1抗体
hz-9235R CDX1 尾侧型同源转录因子1抗体
hz-9236R CDX2/3 尾侧型同源转录因子2/3抗体
hz-9237R RNF35 环指蛋白35抗体
hz-9238R RNF23 环指蛋白23抗体
hz-9239R RNF24 环指蛋白24抗体
hz-9240R RNF25 环指蛋白25抗体
hz-9241R RNF31/HOIP 环指蛋白31抗体
hz-9242R RNF34 环指蛋白34抗体
hz-9243R RNF20 环指蛋白20抗体
hz-9244R RNF21 环指蛋白21抗体
hz-9245R RNF190 环指蛋白190抗体
hz-9246R RNF19B 环指蛋白19B抗体
hz-9247R RNF111 环指蛋白111抗体
hz-9248R RNF113A 环指蛋白113A抗体
hz-9249R RNF123 环指蛋白123抗体
hz-9250R TRAC1/RNF125 环指蛋白125抗体
hz-9251R RNF128 环指蛋白128抗体
hz-9252R RNF130/ 环指蛋白130抗体
hz-9253R RNF133 环指蛋白133抗体
hz-9254R RNF138 环指蛋白138抗体