英文名称    phospho-C5R1 (Ser338)    

中文名称    磷酸化补体成分5受体1抗体    

别    名    C5R1 (phospho S338); p-C5R1 (phospho S338); ANAPHYLATOXIN RECEPTOR; C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin receptor; C5A; C5a ligand; C5a-R; C5aR; C5AR_HUMAN; c5ar1; C5R1; CD88; CD88 antigen; Complement component 5 receptor 1; Complement component 5 receptor 1; Complement component 5 receptor 2; Complement component 5a receptor 1.    

说 明 书    0.1ml      

产品类型    磷酸化抗体     

研究领域    肿瘤  细胞生物  免疫学  信号转导  新陈代谢  G蛋白信号      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 磷酸化补体成分5受体1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    39kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthesised phosphopeptide derived from human C5R1 around the phosphorylation site of (Ser338).    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

磷酸化补体成分5受体1抗体产品介绍    background:

CD88, also known as C5a receptor (C5aR), is a G protein-coupled integral membrane protein. CD88, which is expressed on neutrophils, monocytes, macrophages, hepatocytes and mast cells, as well as on various epithelial and endothelial cells, serves as a receptor for the inflammatory peptide C5a. Research studies suggest a role for CD88 in the inflammatory response. The binding of C5a to CD88 has been shown to elicit increased production of acute phase proteins in liver. In brain, an increased production of CD88 has been shown to be associated with inflammation. Research also indicates a role for C5a/C5aR in the pathogenesis of rheumatoid arthritis, as well as a heightened responsiveness of human bronchial epithelial cells (HBECs) to C5a upon exposure of these cells to cigarette smoke and other environmental irritants.

Function:
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.    

磷酸化补体成分5受体1抗体

hz-0358D-AF647 Donkey Anti-Guinea pig IgG/Alexa Fluor 647  Alexa Fluor 647标记的驴抗豚鼠IgG

hz-0358D-PE-hzy5.5 Donkey Anti-Guinea pig IgG/PE-Cy5.5  PE-Cy5.5标记的驴抗豚鼠IgG

hz-0358D-PE-hzy7 Donkey Anti-Guinea pig IgG/PE-Cy7  PE-Cy7标记的驴抗豚鼠IgG

hz-0358D-FIThz Donkey Anti-Guinea pig IgG/FITC  FITC标记的驴抗豚鼠IgG

hz-0358D-RBIThz Donkey Anti-Guinea pig IgG/RBITC  罗丹明标记的驴抗豚鼠IgG

hzm-0297M-RBIThz Mouse Anti-human IgG(3D3)/RBITC  罗丹明标记的鼠抗人IgG单克隆抗体

hzm-0297M-FIThz Mouse Anti-human IgG(3D3)/FITC  FITC标记的鼠抗人IgG单克隆抗体

hzm-0297M-Gold Mouse Anti-human IgG(3D3)/Gold  胶体金标记的鼠抗人IgG单克隆抗体

hzm-0297M-hzy3 Mouse Anti-human IgG(3D3)/Cy3  Cy3标记的鼠抗人IgG单克隆抗体

hzm-0297M-hzy5 Mouse Anti-human IgG(3D3)/Cy5  Cy5标记的鼠抗人IgG单克隆抗体

hzm-0297M-hzy5.5 Mouse Anti-human IgG(3D3)/Cy5.5  Cy5.5标记的鼠抗人IgG单克隆抗体

hzm-0297M-hzy7 Mouse Anti-human IgG(3D3)/Cy7  Cy7标记的鼠抗人IgG单克隆抗体

hzm-0297M-PE Mouse Anti-human IgG(3D3)/PE  PE标记的鼠抗人IgG单克隆抗体

hzm-0297M-PE-hzy3 Mouse Anti-human IgG(3D3)/PE-Cy3  PE-Cy3标记的鼠抗人IgG单克隆抗体

hzm-0297M-PE-hzY5 Mouse Anti-human IgG(3D3)/PE-CY5  PE-CY5标记的鼠抗人IgG单克隆抗体

hzm-0297M-APhz Mouse Anti-human IgG(3D3)/APC  APC标记的鼠抗人IgG单克隆抗体

hzm-0297M-AF350 Mouse Anti-human IgG(3D3)/Alexa Fluor 350  Alexa Fluor 350标记的鼠抗人IgG单克隆抗体

hzm-0297M-AF488 Mouse Anti-human IgG(3D3)/Alexa Fluor 488  Alexa Fluor 488标记的鼠抗人IgG单克隆抗体

hzm-0297M-AF555 Mouse Anti-human IgG(3D3)/Alexa Fluor 555  Alexa Fluor 555标记的鼠抗人IgG单克隆抗体

hzm-0297M-AF647 Mouse Anti-human IgG(3D3)/Alexa Fluor 647  Alexa Fluor 647标记的鼠抗人IgG单克隆抗体

hzm-0297M-PE-hzy5.5 Mouse Anti-human IgG(3D3)/PE-Cy5.5  PE-Cy5.5标记的鼠抗人IgG单克隆抗体

hzm-0297M-PE-hzy7 Mouse Anti-human IgG(3D3)/PE-Cy7  PE-Cy7标记的鼠抗人IgG单克隆抗体

hzm-0297M-HRP Mouse Anti-human IgG(3D3)/HRP  辣根过氧化物酶标记的鼠抗人IgG单克隆抗体

hzm-0297M-AP Mouse Anti-human IgG(3D3)/AP  碱性磷酸酶（AP）标记的鼠抗人IgG单克隆抗体

hzm-0297M-Bio Mouse Anti-human IgG(3D3)/Bio  生物素标记的鼠抗人IgG单克隆抗体

五、蛋白质与多肽

编  号 名  称

hz-0292P BSA (bovine serum albumin)  牛血清白蛋白（第五组分）

hz-0225P KLH (keyhole limpet hhzocyanin)  血蓝蛋白