产品详情
英文名称 Cezanne
中文名称 Cezanne蛋白抗体
别 名 Cellular zinc finger anti NF kappa B protein; Cellular zinc finger anti-NF-kappa-B protein; CEZANNE; HGNC:16683; OTU domain containing protein 7B; OTU domain containing protein 7B; OTU domain-containing protein 7B; OTU7B_HUMAN; OTUD7B; ZA20D1; Zinc finger A20 domain containing protein 1; Zinc finger A20 domain-containing protein 1; Zinc finger protein Cezanne.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 信号转导 激酶和磷酸酶 表观遗传学 泛素
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 Cezanne蛋白抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 92kDa
细胞定位 细胞核 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cezanne
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 ∑C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20∑C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ∑C.
Cezanne蛋白抗体产品介绍 background:
OTUD7B (OTU domain-containing protein 7B), also known as ZA20D1 or Cezanne, is an 843 amino acid protein that localizes to both the nucleus and the cytoplasm. Expressed in a variety of tissues, including liver, kidney, heart and immature B-cells, OTUD7B functions to hydrolyze branched and linear forms of polyubiquitin, specifically deubiquinating Lys-48- and Lys-63-linked polyubiquitin chains. Via its ability to deubiquinate target proteins, OTUD7B regulates the inflammatory response within the cell and may play a role in cell survival. More specifically, OTUD7B forms a negative feedback loop in pro-inflammatory signaling, thereby suppressing NFⅹB activity and helping to resolve inflammatory responses. OTUD7B contains one C-terminal A20-type zinc finger, one OTU domain and one N-terminal TRAF-binding domain through which it conveys its deubiquitinating activity.
Function:
Has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin. Negative regulator of nuclear factor NF-kappa-B.
Cezanne蛋白抗体
hz-0308P-APhz Horse IgG/APC 荧光素APC标记马IgG
hz-0374P-APhz Horse IgM/APC 荧光素APC标记马IgM
hz-0297P-APhz human IgG/APC 荧光素APC标记人IgG
hz-0345P-APhz human IgM/APC 荧光素APC标记人IgM
hz-0360P-APhz human IgA/APC 荧光素APC标记人IgA
hz-0335P-APhz Monkey IgG/APC 荧光素APC标记猴IgG
hz-0336P-APhz Monkey IgM/APC 荧光素APC标记猴IgM
hz-0368P-APhz Mouse IgM/APC 荧光素APC标记小鼠IgM
hz-0309P-APhz pig IgG/APC 荧光素APC标记猪IgG
hz-0369P-APhz Rabbit IgM/APC 荧光素APC标记兔IgM
hz-0346P-APhz Rat IgM/APC 荧光素APC标记大鼠IgM
hz-0789P-APhz Insulin Protein /APC 荧光素APC标记猪胰岛素蛋白
hz-P0002-APhz KLH/APC 荧光素APC标记血蓝蛋白
hz-P0003-APhz OVA/APC 荧光素APC标记鸡卵白蛋白
hz-0945P-APhz HSA(Human sermu albumin)/APC 荧光素APC标记人血白蛋白
hz-2179P-APhz AACT/APC 荧光素APC标记胰糜蛋白酶
hz-0437P-hzy3 Streptavidin/Cy3 荧光素Cy3标记链霉亲和素
hz-0312P-hzy3 Avidin/Cy3 荧光素Cy3标记亲合素
hz-0362P-hzy3 Protein A/Cy3 Cy3标记蛋白A
hz-0295P-hzy3 Rabbit IgG/Cy3 荧光素Cy3标记兔IgG(细胞流式同型对照)
hz-0296P-hzy3 Mouse IgG/Cy3 荧光素Cy3标记小鼠IgG(细胞流式同型对照)
hz-0294P-hzy3 Goat IgG/Cy3 荧光素Cy3标记羊IgG(细胞流式同型对照)
hz-0293P-hzy3 Rat IgG/Cy3 荧光素Cy3标记大鼠IgG(细胞流式同型对照)
hz-0326P-hzy3 Bovine IgG/Cy3 荧光素Cy3标记牛IgG
hz-0327P-hzy3 Bovine IgM/Cy3 荧光素Cy3标记牛IgM
hz-0310P-hzy3 Chicken IgG/Cy3 荧光素Cy3标记鸡IgG
hz-0314P-hzy3 Chicken IgM/Cy3 荧光素Cy3标记鸡IgM
hz-0303P-hzy3 dog IgG/Cy3 荧光素Cy3标记狗IgG
hz-0373P-hzy3 dog IgM/Cy3 荧光素Cy3标记狗IgM
hz-0370P-hzy3 Goat IgM/Cy3 荧光素Cy3标记羊IgM
hz-0358P-hzy3 Guinea pig IgG/Cy3 荧光素Cy3标记豚鼠IgG
hz-0375P-hzy3 Guinea pig IgM/Cy3 荧光素Cy3标记豚鼠IgM
hz-0308P-hzy3 Horse IgG/Cy3 荧光素Cy3标记马IgG
hz-0374P-hzy3 Horse IgM/Cy3 荧光素Cy3标记马IgM
hz-0297P-hzy3 human IgG/Cy3 荧光素Cy3标记人IgG
hz-0345P-hzy3 human IgM/Cy3 荧光素Cy3标记人IgM