产品详情
英文名称 COPG
中文名称 外壳蛋白COPG-γ抗体
别 名 Coat protein gamma cop; Coatomer protein complex, subunit gamma 1; coatomer protein complex, subunit gamma; Coatomer subunit gamma; Coatomer subunit gamma-1; COP; COPG1; COPG1_HUMAN; FLJ21068; Gamma coat protein; Gamma COP; Gamma-1-coat protein; Gamma-1-COP.
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 信号转导 转运蛋白
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Cow, Horse, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 外壳蛋白COPG-γ抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
细胞定位 细胞浆
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human COPG
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
外壳蛋白COPG-γ抗体产品介绍 background:
Membrane and vesicular trafficking in the early secretory pathway are mediated by non-clathrin COP (coat protein) I-coated vesicles. COPI-coated vesicles mediate retrograde transport from the Golgi back to the ER and intra-Golgi transport. The cytosolic precursor of the COPI coat, the heptameric coatomer complex, is composed of two subcomplexes. The first consists of the COPB, COPG, COPD and COPZ subunits (also known as b-, g-, d- and z-COP, respectively), which are distantly homologous to AP Clathrin adaptor subunits. The second consists of the COPA, b'-COP and COPE subunits (also known as a-COP, COPP and e-COP, r espectively). The COPG (g-COP) subunit of the coatomer is believed to mediate the binding to the cytoplasmic dilysine motifs of membrane proteins. COPG has the highest level of expression in mouse testis and is expressed in a parent-of-origin-specific manner in mammals.
Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis.
外壳蛋白COPG-γ抗体
hz-1170R FOS B FosB蛋白抗体
hz-2572R FPR1 甲酸基肽受体1抗体
hz-1154R FRA1/FOSL1 FRA-1蛋白抗体
hz-5948R CIP2A/p90 Autoantigen 蛋白磷酸酶PP2A癌抑制蛋白抗体
hz-3158R Phospho-FRA1(Ser265) 磷酸化FRA-1蛋白抗体
hz-1188R FRA2/FOSL2 FRA2/FOSL2抗体
hz-4950R ERAS/HRAS2 胚胎干细胞RAS蛋白抗体
hz-5125R Frizzled 7/FZE3 卷曲蛋白FZD7抗体
hz-1675R fowl typhoid and pullorum disease 鸡白痢、鸡伤寒抗体
hz-2358R FOXA2/HNF 3beta 肝细胞核因子3抗体
hz-2585R FOXF1 叉头蛋白F1抗体
hz-1775R FOXJ1/HFH-4 叉头蛋白J1抗体
hz-1275R FoxP1 叉头蛋白P1抗体
hz-2687R FOXM1/HFH 11 叉头蛋白M1抗体
hz-5951R LIMS1 整合素和生长因子样蛋白1抗体
hz-0269R FoxP3 叉头蛋白P3抗体
hz-2537R FOXO1 叉头蛋白O1抗体
hz-3137R Phospho-FoxO1(Thr24)/FoxO3a(Thr32) 磷酸化叉头蛋白家族抗体
hz-3141R Phospho-FoxO1 (Ser319) 磷酸化叉头蛋白家族1抗体
hz-3142R Phospho-FoxO1 (Ser256) 磷酸化叉头蛋白家族1抗体
hz-1548R FOXO3A 叉头蛋白O3A抗体
hz-3138R Phospho-FoxO3a (Ser318/321) 磷酸化叉头蛋白3A抗体
hz-3139R Phospho-FoxO3a (Ser294) 磷酸化叉头蛋白3A抗体
hz-3140R Phospho-FoxO3a (Ser253) 磷酸化叉头蛋白3A抗体
hz-2766R FOXO4 叉头蛋白O4抗体
hz-3143R Phospho-FoxO4 (Ser193) 磷酸化叉头蛋白4抗体
hz-3144R phospho-FOXO4 (Ser197) 磷酸化叉头蛋白4抗体
hz-3145R phospho-FOXO4 (Ser262) 磷酸化叉头蛋白4抗体
hz-3654R FPRL1/RFP/Lipoxin A4 receptor 脂氧素受体1抗体
hz-0886R Measles virus fusion protein 麻疹病毒融合蛋白抗体
hz-5952R POMT1 蛋白甘露糖基转移酶1抗体
hz-5953R RALA Ras样蛋白A抗体
hz-0507R TBX2/T-box2 血栓素B2抗体(一种新发现的抑癌基因)
hz-0895R FSH receptor 促卵泡刺激素受体抗体
hz-1773R Follistatin 卵泡抑素抗体
问商家