英文名称    DOK1    

中文名称    D酪氨酸激酶衰减蛋白1抗体    

别    名    docking protein 1 (downstream of tyrosine kinase 1); Docking protein 1 (p62(dok)) (Downstream of tyrosine kinase 1) (pp62).; docking protein 1 62kD (downstream of tyrosine kinase 1); Docking protein 1 62kD; Docking protein 1 62kD; Docking protein 1; DOK 1; DOK1; DOK-1; DOK1_HUMAN; Downstream of tyrosine kinase 1; p62(dok); P62DOK; pp62; pp62.    

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  心血管  信号转导  G蛋白偶联受体      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 D酪氨酸激酶衰减蛋白1抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    53kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human DOK1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

D酪氨酸激酶衰减蛋白1抗体产品介绍    background:

The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

Function:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.    

D酪氨酸激酶衰减蛋白1抗体

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hz-6848R Fascin/Actin bundling protein  肌动蛋白结合蛋白Fascin抗体

hz-6849R SLPI/ALK1  分泌型白细胞蛋白酶抑制因子抗体

hz-6850R TPST1  酪蛋白硫酸转移酶1抗体

hz-6851R TPST2  酪蛋白硫酸转移酶2抗体

hz-6852R AGPA/Alpha 1 Acid Glycoprotein  α1酸性糖蛋白1/类粘蛋白1抗体

hz-6853R PIWIL4  piwi样4蛋白抗体

hz-6854R CARD7/NALP1  凋亡加强结构域蛋白7抗体

hz-6855R NALP4  癌/睾丸抗原58抗体

hz-6856R NLRP10  富含亮氨酸重复结构域蛋白10抗体

hz-6857R beta COP  β衣被蛋白抗体

hz-6858R Caspase 4/Caspase 11  半胱胺酸蛋白酶4/11抗体

hz-6859R Caspase 14  半胱胺酸蛋白酶蛋白14抗体

hz-6860R Caspase 5  半胱胺酸蛋白酶蛋白5抗体

hz-6861R Fhz1A  前列腺素E受体4相关蛋白抗体

hz-6862R LANPL  富含亮氨酸样酸性核蛋白抗体

hz-6863R MALT1  粘膜相关淋巴组织淋巴瘤转运蛋白1抗体

hz-6864R NALP12  NALP12抗体

hz-6865R NALP6  富含亮氨酸重复结构域蛋白6抗体

hz-6866R NLRP7  富含亮氨酸重复结构域蛋白7抗体

hz-6867R NLRP9  富含亮氨酸重复结构域蛋白9抗体

hz-6868R ARMER  ARMER抗体

hz-6869R HBXIP  乙型肝炎病毒X蛋白相互作用蛋白

hz-6870R ILP2  抑制细胞凋亡样蛋白2抗体

hz-6871R Interferon alpha 6  干扰素α6抗体

hz-6872R Rffl/RING finger protein 189  环指蛋白189抗体

hz-6873R CERKL  视网膜色素变性蛋白26抗体

hz-6874R Catalase  过氧化氢酶抗体

hz-6875R Adenylate kinase 2/AK2  腺苷酸激酶1抗体

hz-6876R FMRP/FMR1  脆性X智力低下蛋白抗体

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