产品详情
英文名称 DR5
中文名称 肿瘤细胞调亡素/死亡受体5抗体
别 名 Death receptor 5; CD 262; CD262; CD262 antigen; Death domain containing receptor for TRAIL/Apo2L; Death receptor 5; DR 5; DR5; Fas like protein precursor; KILLER; KILLER/DR5; p53 regulated DNA damage inducible cell death receptor (killer); TNF related apoptosis inducing ligand receptor 2; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL R2; TRAIL receptor 2; TRAILR2; TRANCER; TRICK2; TRICK2A; TRICK2B; TRICKB; Tumor necrosis factor receptor like protein ZTNFR9; Tumor necrosis factor receptor superfamily member 10b; ZTNFR9.
规格价格 0.1ml/600元 购买 0.2ml/1000元 购买
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 免疫学 细胞凋亡 细胞膜受体
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DR5 C-terminus
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
生 产 商 BIOSS
PubMed PubMed
产品介绍 background:
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
Function:
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
英文名称 DR5
中文名称 肿瘤细胞调亡素/死亡受体5抗体
别 名 Death receptor 5; CD 262; CD262; CD262 antigen; Death domain containing receptor for TRAIL/Apo2L; Death receptor 5; DR 5; DR5; Fas like protein precursor; KILLER; KILLER/DR5; p53 regulated DNA damage inducible cell death receptor (killer); TNF related apoptosis inducing ligand receptor 2; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TRAIL R2; TRAIL receptor 2; TRAILR2; TRANCER; TRICK2; TRICK2A; TRICK2B; TRICKB; Tumor necrosis factor receptor like protein ZTNFR9; Tumor necrosis factor receptor superfamily member 10b; ZTNFR9.
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 免疫学 细胞凋亡 细胞膜受体
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500肿瘤细胞调亡素/死亡受体5抗体 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DR5 C-terminus
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
肿瘤细胞调亡素/死亡受体5抗体产品介绍 background:
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
Function:
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
肿瘤细胞调亡素/死亡受体5抗体
hz-7534R PGC1 beta 过氧化物酶体增殖物激活受体γ辅激活子1β抗体
hz-7535R PGC1 alpha + beta 过氧化物酶体增殖物激活受体γ辅激活子1α+β抗体
hz-7536R SERPINA12/Vaspin 内脏脂肪组织源性丝氨酸蛋白酶抑制蛋白抗体
hz-7537R SIRT4/SIR 2 like protein 4 沉默调节相关蛋白4抗体
hz-7538R TRIB3/p65 interacting inhibitor of NF-kappaB 神经细胞死亡诱导蛋白激酶抗体
hz-7539R SERCA1 ATPase 肌浆/内质网钙ATP酶1抗体
hz-7540R GRK5 G蛋白偶联受体激酶5抗体
hz-7541R EDG3 内皮分化型G蛋白偶联受体3抗体
hz-7551R TNFAIP3 interacting protein 3/ABIN3 肿瘤坏死因子α诱导相互作用蛋白3抗体
hz-7542R RISC/Serine carboxypeptidase 1 丝氨酸羧肽酶1抗体
hz-2731R APS APS抗体
hz-7544R SOAT1/ACAT1 胆固醇酰基转移酶1抗体
hz-3003R phospho-APS(Ser598) 磷酸化APS抗体
hz-7545R Scavenger Receptor BII 清道夫受体B2抗体
hz-7546R CD239 B细胞粘附分子CD239抗体
hz-3569R AP2 alpha 转录激活蛋白2α抗体
hz-7547R CPB2/Carboxypeptidase B2 胰羧肽酶B2抗体
hz-7548R Fibrinopeptide A 纤维蛋白肽A/血纤肽抗体
hz-7549R GAS 6 生长停滞特异性蛋白6抗体
hz-7550R AUP1/Ancient ubiquitous protein 1 原始广泛存在蛋白1抗体
hz-7552R Biglycan 骨/软骨蛋白多糖1抗体
hz-2532R ALT1 谷丙氨酸氨基转移酶1抗体
hz-7553R Eph receptor A2+A3+A4 内皮细胞受体蛋白酪氨酸激酶A2+A3+A4抗体
hz-7554R phospho-Eph receptor A2+A3+A4 (Tyr588 + Tyr596) 磷酸化内皮细胞受体蛋白酪氨酸激酶A2+A3+A4抗体
hz-7555R phospho-EPH A3+A4+A5 ( Tyr779) 磷酸化内皮细胞受体蛋白酪氨酸激酶A3+A4+A5抗体
hz-7556R FLAP/5-lipoxygenase activating protein 5脂氧合酶激活蛋白抗体
hz-7557R IKK alpha + IKK beta KB抑制蛋白激酶α/β抗体
hz-7558R MC3 Receptor 黑素皮质素受体3抗体
hz-7559R PDGF AB+BB 血小板源性生长因子AB+BB抗体
hz-7560R CPLA2 胞浆型磷脂酶A2抗体
hz-7561R TIRAP 白细胞介素1受体衔接蛋白抗体
hz-7562R phospho-TIRAP(Tyr86) 磷酸化白细胞介素1受体衔接蛋白抗体
hz-7563R TNIP2/ABIN2/TNFAIP3 interacting protein 2 肿瘤坏死因子α诱导蛋白3相互作用蛋白2抗体
hz-7564R Azurocidin/Cationic antimicrobial protein 37 肝素结合蛋白/阳离子抗菌蛋白37/天青杀素抗体