产品详情
英文名称 DRAM
中文名称 DNA损伤自噬调整蛋白抗体
别 名 Damage regulated autophagy modulator; Damage-regulated autophagy modulator; DNA damage-regulated autophagy modulator protein 1; dram1; DRAM1_HUMAN.
说 明 书 0.1ml 0.2ml
研究领域 肿瘤 心血管 免疫学 细胞凋亡
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
产品应用 IHC-P=1:100-500 IHC-F=1:100-500 DNA损伤自噬调整蛋白抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
细胞定位 细胞浆 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DRAM
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DNA损伤自噬调整蛋白抗体产品介绍 background:
This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4. [provided by RefSeq, Jul 2008]
Function:
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.
Subcellular Location:
Lysosome membrane; Multi-pass membrane protein.
Similarity:
Belongs to the DRAM/TMEM150 family.
Gene ID:
55332
Database links:
Entrez Gene: 55332 Human
Entrez Gene: 71712 Mouse
Omim: 610776 Human
SwissProt: Q8N682 Human
SwissProt: Q9DC58 Mouse
Unigene: 525634 Human
Unigene: 35450 Mouse
DNA损伤自噬调整蛋白抗体
hz-2562R COX7A2 细胞色素c氧化酶7A2抗体
hz-3934R COX3 细胞色素C氧化酶亚基3抗体
hz-2714R COX7A2 细胞色素c氧化酶COX7A2抗体
hz-3935R COX6B 细胞色素C氧化酶亚基6B抗体
hz-3763R Activin A Receptor Type IB 激活素受体1B抗体
hz-0804R ARIP2a 激活素受体2A抗体
hz-0857R Beta-arrestin 1 β-抑制蛋白1抗体
hz-3048R Phospho-beta-Arrestin 1(Ser412) 磷酸化β抑制蛋白1抗体
hz-1332R β-arrestin/ARRB2 β-抑制蛋白2抗体/β休止蛋白2抗体
hz-0801R ARIP2B 激活素受体2B抗体
hz-5027R ARP4 肝血管生成素相关蛋白抗体
hz-4006R ARSA 芳基硫酸酯酶A抗体
hz-0055R Arthzin Arthzin抗体
hz-0600R ADRA1/ADRA1B/alpha 1 Adrenergic Receptor alpha 1肾上腺素能受体抗体
hz-11001R FAM61B/LSM14B FAM61B蛋白抗体
hz-11002R ESYT1/FAM62A 延伸突触蛋白1抗体
hz-11003R ESYT2/FAM62B 延伸突触蛋白2抗体
hz-11004R FAM63A FAM63A蛋白抗体
hz-11005R RCS1/FAM64A 染色体分离调节蛋白1抗体
hz-11006R FAM70A FAM70A蛋白抗体
hz-11007R FAM71A FAM71A蛋白抗体
hz-11008R FAM71A FAM71A蛋白抗体
hz-11009R FAM83F FAM83F蛋白抗体
hz-11010R NSE1/FAM84A 感觉神经蛋白1抗体
hz-11011R FAM92A1 FAM92A1蛋白抗体
hz-11012R FAM98A FAM98A蛋白抗体
hz-11013R ILDR1 免疫球蛋白样结构域受体1抗体
hz-11014R ILVBL 乙酰乳酸合成酶蛋白抗体
hz-11015R BFSP2/Phakinin 晶状体蛋白2抗体
hz-11016R GFAP delta 胶质纤维酸性蛋白GFAPδ抗体
hz-11017R NPTX2 神经细胞穿透素2抗体
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