产品详情
英文名称 DISP2
中文名称 转运蛋白DISP2抗体
别 名 DISP 2; Dispatched B; Dispatched homolog 2 (Drosophila); Dispatched homolog 2; DISPB; DKFZp547N223; HsT16908; KIAA1742; Protein dispatched homolog 2; DISP2_HUMAN.
说 明 书 0.2ml
研究领域 肿瘤 细胞生物 信号转导 转录调节因子 细胞表面分子 表观遗传学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 转运蛋白DISP2抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 152kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DISP2 (1101-1200aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
转运蛋白DISP2抗体产品介绍 background:
DISP2 is the second of three known homologs of the D.melanogaster protein Dispatched. It is a multitransmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the DISP proteins have been implicated in these pathways. Recently, it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants. At least two isoforms of DISP2 are known to exist.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Similarity:
Belongs to the dispatched family.
Contains 1 SSD (sterol-sensing) domain.
Database links:
UniProtKB/Swiss-Prot: A7MBM2.2
转运蛋白DISP2抗体
hz-0309R-AF488 Rabbit Anti-pig IgG/Alexa Fluor 488 Alexa Fluor 488标记的兔抗猪IgG
hz-0309R-AF350 Rabbit Anti-pig IgG/Alexa Fluor 350 Alexa Fluor 350标记的兔抗猪IgG
hz-0309R-PE-hzy3 Rabbit Anti-pig IgG/PE-Cy3 PE-Cy3标记的兔抗猪IgG
hz-0309R-PE-hzY5 Rabbit Anti-pig IgG/PE-CY5 PE-CY5标记的兔抗猪IgG
hz-0309R-APhz Rabbit Anti-pig IgG/APC APC标记的兔抗猪IgG
hz-0309R-AF647 Rabbit Anti-pig IgG/Alexa Fluor 647 Alexa Fluor 647标记的兔抗猪IgG
hz-0309R-PE-hzy5.5 Rabbit Anti-pig IgG/PE-Cy5.5 PE-Cy5.5标记的兔抗猪IgG
hz-0309R-PE-hzy7 Rabbit Anti-pig IgG/PE-Cy7 PE-Cy7标记的兔抗猪IgG
hz-0309R-hzy3 Rabbit Anti-pig IgG/Cy3 Cy3标记的兔抗猪IgG
hz-0309R-hzy5 Rabbit Anti-pig IgG/Cy5 Cy5标记的兔抗猪IgG
hz-0309R-hzy5.5 Rabbit Anti-pig IgG/Cy5.5 Cy5.5标记的兔抗猪IgG
hz-0309R-hzy7 Rabbit Anti-pig IgG/Cy7 Cy7标记的兔抗猪IgG
hz-0309R-PE Rabbit Anti-pig IgG/PE PE标记的兔抗猪IgG
hz-0403R-hzy5.5 Rabbit anti-MG IgG/Cy5.5 Cy5.5标记的兔抗长爪沙鼠IgG
hz-0403R-hzy7 Rabbit anti-MG IgG/Cy7 Cy7标记的兔抗长爪沙鼠IgG
hz-0403R-RBIThz Rabbit anti-MG IgG/RBITC 罗丹明标记的兔抗长爪沙鼠IgG
hz-0403R-FIThz Rabbit anti-MG IgG/FITC FITC标记的兔抗长爪沙鼠IgG
hz-0403R-Bio Rabbit anti-MG IgG/Bio 生物素标记的兔抗长爪沙鼠IgG
hz-0403R-hzy3 Rabbit anti-MG IgG/Cy3 Cy3标记的兔抗长爪沙鼠IgG
hz-0403R-hzy5 Rabbit anti-MG IgG/Cy5 Cy5标记的兔抗长爪沙鼠IgG
hz-0403R-PE Rabbit anti-MG IgG/PE PE标记的兔抗长爪沙鼠IgG
hz-0403R-PE-hzy3 Rabbit anti-MG IgG/PE-Cy3 PE-Cy3标记的兔抗长爪沙鼠IgG
hz-0403R-PE-hzY5 Rabbit anti-MG IgG/PE-CY5 PE-CY5标记的兔抗长爪沙鼠IgG
hz-0403R-PE-hzy7 Rabbit anti-MG IgG/PE-Cy7 PE-Cy7标记的兔抗长爪沙鼠IgG
hz-0403R-APhz Rabbit anti-MG IgG/APC APC标记的兔抗长爪沙鼠IgG
hz-0403R-AF350 Rabbit anti-MG IgG/Alexa Fluor 350 Alexa Fluor 350标记的兔抗长爪沙鼠IgG
hz-0403R-AF488 Rabbit anti-MG IgG/Alexa Fluor 488 Alexa Fluor 488标记的兔抗长爪沙鼠IgG
hz-0403R-AF555 Rabbit anti-MG IgG/Alexa Fluor 555 Alexa Fluor 555标记的兔抗长爪沙鼠IgG
hz-0403R-AF647 Rabbit anti-MG IgG/Alexa Fluor 647 Alexa Fluor 647标记的兔抗长爪沙鼠IgG