产品详情
英文名称 DSS1
中文名称 先天性裂手/裂足畸形相关蛋白DSS1抗体
别 名 26S proteasome complex subunit DSS1; Deleted in split hand/split foot 1; Deleted in Split-Hand/Split-Foot 1 region; ECD; SEM1; SHFD1; DSS1_HUMAN; SHFM1; SHSF1; Split hand/foot deleted protein 1; Split hand/foot malformation (ectrodactyly) type 1; Split hand/foot malformation type 1 protein.
说 明 书 0.2ml
研究领域 细胞生物 发育生物学 细胞周期蛋白 泛素
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Pig, Cow, Rabbit,
产品应用 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 先天性裂手/裂足畸形相关蛋白DSS1抗体(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 8.3kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human DSS1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
先天性裂手/裂足畸形相关蛋白DSS1抗体产品介绍 background:
The product of this gene has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle. [provided by RefSeq, Jul 2008]
Function:
The gene for DSS1 has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. DSS1 has been proposed to be a candidate for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle.
Subunit:
Part of the 26S proteasome. Interacts with the C-terminal of BRCA2.
Tissue Specificity:
Expressed in limb bud, craniofacial primordial and skin.
Similarity:
Belongs to the DSS1/SEM1 family.
Gene ID:
7979
Database links:
Entrez Gene: 7979 Human
Omim: 601285 Human
SwissProt: P60896 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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