英文名称    DUSP19    

中文名称    双特异性磷酸酶抗体19抗体    

别    名    Dual specificity phosphatase 19; Dual specificity phosphatase TS DSP1; Dual specificity phosphatase TS-DSP1; Dual specificity protein phosphatase 19; DUS19_HUMAN; DUSP 17; DUSP 19; DUSP17; Dusp19; LMW DSP3; LMW-DSP3; LMWDSP 3; LMWDSP3; Low molecular weight dual specificity phosphatase 3; MGC138210; Protein phosphatase SKRP1; SAPK pathway regulating phosphatase 1; SAPK pathway-regulating phosphatase 1; SKRP 1; SKRP1; Stress activated protein kinase pathway regulating phosphatase 1; Stress-activated protein kinase pathway-regulating phosphatase 1; TS DSP1.    

说 明 书    0.2ml      

研究领域    细胞生物  信号转导  激酶和磷酸酶      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 双特异性磷酸酶抗体19抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    18, 24kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human DUSP19    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

双特异性磷酸酶抗体19抗体产品介绍    background:

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]

Function:
Has a dual specificity toward Ser/Thr and Tyr-containing proteins.

Tissue Specificity:
Expressed in the heart, lung, liver, and pancreas. The expression level in the pancreas is the highest.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 tyrosine-protein phosphatase domain.

Gene ID:
142679

Database links:

Entrez Gene: 142679 Human

Entrez Gene: 68082 Mouse

Entrez Gene: 311151 Rat

Omim: 611437 Human

SwissProt: Q547H4 Human

SwissProt: Q8WTR2 Human

SwissProt: Q8K4T5 Mouse

Unigene: 132237 Human

Unigene: 306818 Mouse

Unigene: 65563 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

双特异性磷酸酶抗体19抗体

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hz-7880R MEGF5/Slit3  复合型表皮生长因子样结构域蛋白5抗体

hz-7881R TRIM29/ATDC  共济失调毛细血管扩张症D相关蛋白抗体

hz-7882R UBE2V1/UEV1A  泛素结合酶E2变异体1抗体

hz-7883R VHLH/Von Hippel Lindau  脑视网膜血管瘤G7蛋白抗体（逢希伯-林道氏病）

hz-7884R Cyclin B3  周期素B3抗体

hz-7885R CCNDBP1/GCIP  周期素D结合蛋白1抗体

hz-7886R AFF4  淋巴细胞相关AF4样蛋白抗体

hz-7887R Cyclin K/CCNK  周期素K抗体

hz-7888R Cyclin L/CCNL1  周期素L抗体

hz-7889R CCNYL1  周期素样Y1抗体

hz-7890R Cyclin J  周期素J抗体

hz-7891R Cyclin T2  周期素T2抗体

hz-7892R AIMP3/p18  抑癌蛋白AIMP3抗体

hz-7893R CABLES1  细胞周期蛋白依赖性激酶CABLES1抗体

hz-7894R CDCA3  细胞分裂周期相关蛋白3抗体

hz-7895R DBF4A  S期激酶活化蛋白DBF4A抗体

hz-3765R SAP/Serum Amyloid P  血清淀粉样蛋白P成份抗体

hz-7896R MNAT1  细胞周期G1的相互作用蛋白抗体

hz-7897R CDC2L5  细胞分裂周期2样蛋白激酶5抗体

hz-7898R PICK1  蛋白激酶Cα相互作用蛋白1抗体

hz-7899R INCA1  INCA1蛋白抗体

hz-7900R MS4A3/CD20L  CD20样蛋白抗体（造血干细胞4跨膜蛋白3）

hz-0057R Amylin  糖尿病相关肽/胰岛淀粉样肽抗体

hz-7901R SPDYA  细胞周期G2/M期快速诱导蛋白SPDYA抗体

hz-7902R phospho-FRS2(Tyr436)  磷酸化成纤维细胞生长因子受体底物2抗体

hz-7903R ASP/AKAP associated Sperm Protein  精子相关蛋白AKAP抗体

hz-7904R AKAP6  蛋白激酶A锚定蛋白6抗体

hz-7905R BRSK1  丝氨酸/苏氨酸蛋白激酶SAD-B抗体

hz-7906R CERK  神经酰胺激酶CERK抗体

hz-7907R CLK2  细胞分裂周期样激酶2抗体