英文名称    DUSP9    

中文名称    双特异性磷酸酶抗体9抗体    

别    名    Dual specificity phosphatase 9; Dual specificity protein phosphatase 9; DUS9_HUMAN; DUSP9; MAP kinase phosphatase 4; Mitogen activated protein kinase phosphatase 4; Mitogen-activated protein kinase phosphatase 4; MKP 4; MKP-4; MKP4; serine/threonine specific protein phosphatase.    

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导  激酶和磷酸酶      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 双特异性磷酸酶抗体9抗体（石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    42kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human DUSP9    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

双特异性磷酸酶抗体9抗体产品介绍    background:

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus. [provided by RefSeq, Jul 2008]

Function:
Inactivates MAP kinases. Has a specificity for the ERK family.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 rhodanese domain.
Contains 1 tyrosine-protein phosphatase domain.

Gene ID:
1852

Database links:

Entrez Gene: 1852 Human

Entrez Gene: 614306 Cow

Entrez Gene: 75590 Mouse

Entrez Gene: 293847 Rat

Omim: 300134 Human

SwissProt: Q99956 Human

Unigene: 144879 Human

Unigene: 16479 Mouse

Unigene: 100548 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

双特异性磷酸酶抗体9抗体

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